Synthesis and antimicrobic properties of substituted 2,3-trimethylenethiazolium salts and certain thiocyanin dyes

The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

“…Various ring systems containing the moiety -C(SH)=N- as a part of the ring have been found to condense with α-haloketones to yield pyrrolo[2,1- b ]thia-zoles [ 330 ], thiazolo[3,2- b ]isothiazolines [ 331 ], thiazolo[3,2- b ]-1,2,4-triazoles [ 332 , 333 ], thiazolo[3,2- d ]tetrazoles [ 334 ], thiazolo[3,2- a ]- pyridines [ 335 ], thiazolo[3,2- a ]pyrimid-ines [ 336 , 337 , 338 , 339 ], thiazolo[3,2- a ]-1,3,5-triazines [ 340 ], thiazolo-[3,2- b ]tetrazines [ 341 , 342 ], and thiazolo[ 1 , 2 , 4 ]triazepines [ 343 ]. Scheme 38 represents an example for preparation of such condensed systems.…”

The Chemistry of α‐Haloketones and Their Utility in Heterocyclic Synthesis

“…Thiazole-2-thiones 135 could be synthesized according to the method of Sandstrom [322,323]. The reaction of primary alkyl, aryl or heterocyclic amines 132 with carbon disulfide in dry DMF, Various ring systems containing the moiety -C(SH)=N-as a part of the ring have been found to condense with α-haloketones to yield pyrrolo[2,1-b]thiazoles [330], thiazolo [3,2- [332,333], thiazolo [3,2-d]tetrazoles [334], thiazolo[3,2-a]pyridines [335], thiazolo[3,2-a]pyrimidines [336][337][338][339], thiazolo[3,2-a]-1,3,5-triazines [340], thiazolo-[3,2-b]tetrazines [341][342], and thiazolo [1,2,4]triazepines [343]. Scheme 38 represents an example for preparation of such condensed systems.…”