Synthesis and antimicrobial studies of new pyridine derivatives

Synthesis and Heteroannulation of Pyridine and Related Heterocyclic Systems Having Surface and Biological Activities

“…A large number of heterocyclic compounds containing pyridine rings are associated with diverse pharmacological properties such as antimicrobial 15,16 , anticancer 17 anticonvulsant 18 , antiviral 19 , anti-HlV 20 , antifungal and antimycobacterial activities 21 . The pyridine heterocycle continues to play a vital role in the development of human medicines.…”

“…Fatty acids containing hetero atoms are regarded as surface and potential antimicrobial agents 33,34 . Thus, the use of fatty acid substrates as starting materials has become significant because of their own biological activity 16 . So, the fatty acids on derivatization to these heterocyclic compounds can be used as valuable oleo-chemicals 35,36 .…”

Synthesis and antimicrobial activity of pyrazolinones and pyrazoles having benzothiazole moiety

“…1). Moreover, a recent study showed that chloro substitution at 6th position of benzothiazole moiety led to maximal antimicrobial activity (Patel and Agravat, 2009). Furthermore, pyrazoles and pyrazolinones have also emerged as a group of compounds possessing a broad spectrum of useful medicinal properties such as anti-inflammatory (Amir et al, 2008a), anticancer (Cheng et al, 2010;Demirayak et al, 2010), anti-tubercular (Castagnolo et al, 2009), and antimicrobial activities (Gouda et al, 2010;Ragavan et al, 2010;Ozdemir et al, 2010;Anand and Remers, 2003) (Fig.…”

Synthesis and Microbial Studies of New Pyridine Derivatives‐III

“…14,15 Prompted by recent literature observations and as a part of our search for biologically active compounds, we have continued our previous work on reactions of 2-chloropyridine-3-carboxylic acid [16][17][18][19] with substituted benzothiazoles and piperazines. The search for new, effective and safe nuclei has led to an improvement by increasing their potency.…”