Synthesis and Antimicrobial Investigation of Some Novel Phenyl Pyrazole, Azetidinone and Diazenyl Ethanone Derivatives of Benzofurans.

Abstract

Twenty title compounds such as (V), (IX), or (XI) are screened for their antimicrobial and antifungal effects. Some derivatives of type (IX), e.g. derivative (IXb), show significant activities. -(KUMAR, D. B. A.; PRAKASH, G. K.; KUMARASWAMY, M. N.; NANDESHWARAPPA, B. P.; SHERIGARA, B. S.; MAHADEVAN*, K. M.; Indian

Solvent-free microwave-assisted synthesis ofE-(1)-(6-benzoyl-3,5-dimethylfuro[3′,2′:4,5]benzo[b]furan-2-yl)-3-(aryl)-2-propen-1-ones and their antibacterial activity

“…IR spectra were recorded on Shimadzu FTIR-8400s spectrophotometer. 1 H NMR and 13 C NMR spectra were recorded on Avance 300 spectrometer, and mass spectra were recorded on Shimadzu mass spectrometer. Elemental analysis was determined by using ThermoFinnigan CHNS analyzer.…”

Pyrrolizine/indolizine-bearing (un)substituted isoindole moiety: design, synthesis, antiproliferative and MDR reversal activities, and in silico studies

“…A literature survey showed that the acetanilide derivatives 2a-f were obtained through acylation of the appropriate amines with chloroacetyl chloride using different reaction conditions such as triethylamine, potassium carbonate, sodium acetate or pyridine in different solvents such as glacial acetic acid, dichloromethane, DMF or acetone. [43][44][45][46] In this study, the acetanilide derivatives 2a-f were synthesized with good yield using acetic acid and sodium acetate according to the method by Kumar et al 47 On the other hand, intermediates 4a and b were synthesized by reacting 2-pyrrolidinone 3a or 2-piperidinone 3b with malononitrile in dry benzene via condensation reaction. 48 These intermediates were conrmed by their melting points, as reported.…”

Synthesis and molluscicidal evaluation of some new pyrazole, isoxazole, pyridine, pyrimidine, 1,4-thiazine and 1,3,4-thiadiazine derivatives incorporating benzofuran moiety

“…2-Acetylbenzofuran (1) and 3-(benzofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (2) [12] reacted in the presence of aqueous sodium hydroxide yielded the 1,3-disubstituted prop-2-en-1-one derivative 3. Bromonation of 3 with bromine in chloroform yielded 2,3-dibromo-1,3-disubstituted propan-1-one 4 in good yield.…”