Synthesis and Antimicrobial Applications of ZnO Nanostructures: A Review

Izzi, Margherita; Sportelli, Maria Chiara; Torsi, Luisa; Picca, Rosaria Anna; Cioffi, Nicola

doi:10.1021/acsanm.3c01432

Cited by 22 publications

(13 citation statements)

References 295 publications

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“…Moreover, ZnO nanostructures have been demonstrated to execute antifungal, antimicrobial, and antibacterial activities. 87 These particles can be dissolved into Zn(II) ions under slightly acidic conditions, and upon irradiation with electromagnetic radiation, ZnO produces reactive oxygen species that change the metabolic cycles of the fungi, bacteria, and microbes. The nanostructures can undergo electrostatic interactions with the cell wall that cause rupturing of the microbial membrane.…”

Section: Crystallinity and Applicationsmentioning

confidence: 99%

“…Once inside the cell, the small particulates dissolve under physiological pH conditions and therefore produce reactive oxygen species that disturb the protein activity balance and induce oxidative stress, resulting in the ablation of cancerous cells. Moreover, ZnO nanostructures have been demonstrated to execute antifungal, antimicrobial, and antibacterial activities . These particles can be dissolved into Zn(II) ions under slightly acidic conditions, and upon irradiation with electromagnetic radiation, ZnO produces reactive oxygen species that change the metabolic cycles of the fungi, bacteria, and microbes.…”

Section: Crystallinity and Applicationsmentioning

confidence: 99%

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Growth of ZnO Polytypes: Multiple Facets of Diverse Applications

Debnath,

Sen,

Neog

et al. 2024

Crystal Growth & Design

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Zinc oxide has been considered as a specific and versatile bridging agent that bears an intrinsic relationship with the crystal structure−property application in physics, chemistry, materials, and biomedical sciences. Due to inherent polytypism through the abundance of crystal structures, the properties can interconnect from classical (bulk structures) to quantum (nanostructures) regimes that have been the subject of immense investigation using theoretical, experimental, and simulation perspectives. Prudent advances in the synthetic strategies have offered the opportunity to achieve diverse morphologies from ultrasmall to hierarchical superstructures employing chemical manipulation, and the possibility of maneuvering the crystal patterns has marked zinc oxide as an attractive recipe in the buffet of modern materials research. The interplay between the mere variation in the crystalline structures and spatial confinement of ZnO at the nanoscale dimension has become the epicenter of the emergence of unique physicochemical characteristics that can be exploited in a diverse range of niche multifarious applications. Moreover, the ease of syntheses which mostly follow green techniques, cost effectiveness, physical and chemical stability, and biocompatibility have made zinc oxide a semiconductor of great interest in the past three decades. An intrinsic n-type semiconductor with a wide band gap and large exciton binding energy have rendered ZnO as a fundamental material with a synergism of semiconducting, optoelectronic, piezoelectric, pyroelectric, photocatalytic, and biological properties with outstanding industrial and technological applications. The possibility to control the crystallinity through the manipulation of particle shape, size, exposed facets, composition, and doping imbues a diverse range of materials properties that can be tailored to pursue the preconceived applications. Althouth the onset of research with ZnO can be traced back to nearly a century ago, the renewed interest has been rekindled with the accessibility of high-quality single crystals, facile synthesis to various nanostructures, and the availability of p-type ZnO as the cornerstone. Based on these contexts at the backstage, it is now time to condense the large and voluminous work to assess the epicenter of the conceptive, to rationalize the perpectives between crystallographic and physical properties, and to design the objectives to explore the future technological applications in the realm of present major global challenges in the field of energy, environment, and biomedical applications.

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Section: Crystallinity and Applicationsmentioning

confidence: 99%

Section: Crystallinity and Applicationsmentioning

confidence: 99%

Growth of ZnO Polytypes: Multiple Facets of Diverse Applications

Debnath,

Sen,

Neog

et al. 2024

Crystal Growth & Design

View full text Add to dashboard Cite

show abstract

“…Furthermore, the appropriate modifications of ZnO structures such as nanoplatelet, 36 nanowires, 37,38 nanoarrays, 39 nanoparticles, 40 flowers, and nanowalls 41,42 with an active surface area also provided us more choices for particular application. 43 From now, ZnO has gained much attention as one of the utmost promising nanomaterials for the third generation of electrochemical sensors. In contrast, ZnO electrochemical sensors have exposed an enhanced activity, which are designed by the physiochemical properties with 2D base planes, such as −C� N or −N�C� groups through covalent interaction.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, ZnO has an excellent isoelectric point (IPE) about ∼9.5 and to be conductive by decoration/doping into 2D-B-GCN. Furthermore, the appropriate modifications of ZnO structures such as nanoplatelet, nanowires, , nanoarrays, nanoparticles, flowers, and nanowalls , with an active surface area also provided us more choices for particular application . From now, ZnO has gained much attention as one of the utmost promising nanomaterials for the third generation of electrochemical sensors.…”

Section: Introductionmentioning

confidence: 99%

ZnO/B-g-C₃N₄ Nanoplatelet/Nanosheet Heterostructures for the Electrochemical Detection of Metol in Real Sample Analysis

Murugan,

Hwa,

Santhan

et al. 2024

ACS Appl. Nano Mater.

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One of the most important organic molecules is metol [4-(methylamino)phenol sulfate], which finds extensive usage in various applications as a monochromatic material. People, plants, and animals are all affected by it, and it raises serious environmental concerns. Developing a straightforward, quick, affordable, sensitive, and hands-on technique for metol determination in water bodies is of the utmost importance in the current scenario. A low-cost fabrication strategy is presented in this work for the synthesis of a zinc oxide nanoplatelet (ZnO) embedded into boron-doped carbon nitride nanosheet materials (ZnO/2D-BCN) utilizing a high-performance electrochemical sensor. The quantitative and qualitative information about the nanostructure of ZnO/2D-BCN were systematically analyzed further by using standard spectroscopic techniques such as XPS, XRD, FT-IR, EDAX, and Raman spectroscopy. 2D-nonstructural was observed to have a nanoplatelet/nanosheet through FE-SEM and TEM. Furthermore, electrochemical sensors’ performance was analyzed by using cyclic and differential pulsed voltammetry techniques. The fabricated ZnO/2D-BCN has peculiar intrinsic structural features, both connectivity and characteristic synergistic effect of B-dopants 2D-structure, which perturb mass transport with highly efficient electrochemical pathways. In addition, the electrochemical sensors of metol and its electrocatalytic mechanism were scrutinized further, which confirmed a fast electron transfer event. The as-prepared ZnO/2D-BCN exposed superior sensing conclusion through LOD (8.6 nM) in a wide-ranging linear 0.039–1617 (μM) as well as a remarkable sensitivity of 0.804 μA μM–1 cm–2. Additionally, other sensing parameters such as remarkable repeatability, electrodes’ reproducibility, materials’ stability, and a remarkable selectivity toward metol have been performed. Furthermore, the practical feasibility of as-made ZnO/2D-BCN/GCE has been inspected with biological and environment samples such as blood serum, human urine, river, pond, industry, and tap samples as a real sample, revealing excellent rational recovery outcomes.

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“…Extracellular biomass-free production was investigated for many metal nanoparticle investigations of many bacterial strains, such as Bacillus sp., Pseudomonas sp., and Streptomyces sp. 8 . The intermediate stage of research on the biological generation of metallic nanoparticles is being dominated by bacteria due to their ability and tolerance for metal bioaccumulation.…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis and biocompatibility evaluation of zinc oxide nanoparticles prepared using Priestia megaterium bacteria

Ashour,

Abd-Elhalim

2024

Sci Rep

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The current study aimed to find an effective, simple, ecological, and nontoxic method for bacterial green synthesis of zinc oxide nanoparticles (ZnONPs) using the bacterial strain Priestia megaterium BASMA 2022 (OP572246). The biosynthesis was confirmed by the change in color of the cell-free supernatant added to the zinc nitrate from yellow to pale brown. The Priestia megaterium zinc oxide nanoparticles (Pm/ZnONPs) were characterized using UV–Vis spectroscopy, high-resolution transmission electron microscopy (HR-TEM), energy-dispersive X-ray spectroscopy (EDX), Fourier transform infrared spectroscopy (FTIR), and zeta potential. The Pm/ZnONPs characterization showed that they have a size ranging between 5.77 and 13.9 nm with a semi-sphere shape that is coated with a protein-carbohydrate complex. An EDX analysis of the Pm/ZnONPs revealed the presence of the shield matrix, which was composed of carbon, nitrogen, oxygen, chlorine, potassium, sodium, aluminum, sulfur, and zinc. The results of the FTIR analysis showed that the reduction and stabilization of the zinc salt solution were caused by the presence of O–H alcohols and phenols, O=C=O stretching of carbon dioxide, N=C=S stretching of isothiocyanate, and N–H bending of amine functional groups. The produced ZnONPs had good stability with a charge of − 16.2 mV, as evidenced by zeta potential analysis. The MTT assay revealed IC50 values of 8.42% and 200%, respectively, for the human A375 skin melanoma and human bone marrow 2M-302 cell lines. These findings revealed that the obtained Pm/ZnONPs have the biocompatibility to be applied in the pharmaceutical and biomedical sectors.

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Synthesis and Antimicrobial Applications of ZnO Nanostructures: A Review

Cited by 22 publications

References 295 publications

Growth of ZnO Polytypes: Multiple Facets of Diverse Applications

Growth of ZnO Polytypes: Multiple Facets of Diverse Applications

ZnO/B-g-C₃N₄ Nanoplatelet/Nanosheet Heterostructures for the Electrochemical Detection of Metol in Real Sample Analysis

Biosynthesis and biocompatibility evaluation of zinc oxide nanoparticles prepared using Priestia megaterium bacteria

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Synthesis and Antimicrobial Applications of ZnO Nanostructures: A Review

Cited by 22 publications

References 295 publications

Growth of ZnO Polytypes: Multiple Facets of Diverse Applications

Growth of ZnO Polytypes: Multiple Facets of Diverse Applications

ZnO/B-g-C3N4 Nanoplatelet/Nanosheet Heterostructures for the Electrochemical Detection of Metol in Real Sample Analysis

Biosynthesis and biocompatibility evaluation of zinc oxide nanoparticles prepared using Priestia megaterium bacteria

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ZnO/B-g-C₃N₄ Nanoplatelet/Nanosheet Heterostructures for the Electrochemical Detection of Metol in Real Sample Analysis