Synthesis and antimicrobial activity of monodisperse copper nanoparticles

Kruk, Tomasz; Szczepanowicz, Krzysztof; Stefańska, Joanna; Socha, Robert P.; Warszyński, Piotr

doi:10.1016/j.colsurfb.2015.02.009

Cited by 224 publications

(109 citation statements)

References 54 publications

Supporting

Mentioning

104

Contrasting

Unclassified

Order By: Relevance

“…Suspension of CuO NPs by minimum bactericidal concentrations ranging from 100 μg/mL to 5000 μg/mL illustrated antibacterial activity against S. aureus and E. coli [59]. Also, mono-disperse Cu NPs with average diameter 50 nm showed antimicrobial effects on S. sureus (MRSA) and Candida species [60].…”

Section: Antibacterial Activitymentioning

confidence: 99%

Effect of Incubation Time, CuSO4 and Glucose Concentrations on Biosynthesis of Copper Oxide (CuO) Nanoparticles with Rectangular Shape and Antibacterial Activity: Taguchi Method Approach

Rad¹,

Taran²,

Alavi³

2018

Nano BioMed ENG

View full text Add to dashboard Cite

In nanotechnology, using of metallic nanoparticles (MNPs) has obtained major attention for over a century because of their unique properties in nano scale. In this paper, the effect of three factors (incubation time, concentrations of copper sulfate and glucose) on the biosynthesis of copper (II) oxide nanoparticles (CuO NPs) by Halomonas elongata IBRC-M 10214 and the antibacterial activity of nanoparticles were evaluated. Experiment design and analysis of Taguchi method were carried out by Qualitek-4 software. Effect of CuSO4 concentration (1.4, 2.8 and 5.6 mM), incubation time (48, 72 and 96 h) as three different levels was measured as three major factors in the biosynthesis of metallic nanoparticles. Synthesized CuO nanoparticles were characterized by utilizing ultraviolet-visible (UVVis) spectroscopy, X-ray diffraction (XRD), Fourier transform infra-red (FT-IR) spectroscopy and field emission scanning electron microscope (FESEM) techniques. Among the three factors, results illustrated that considerable effect was related to CuSO 4 concentration. These analyses demonstrated that the average CuO nanoparticles crystalline size was 57-79 nm with rectangular shape. Also, for evaluating of antibacterial effects, maximum zone of inhibition, two important multidrug resistant pathogenesis bacteria, Escherichia coli ATCC 25922, and Staphylococcus aureus ATCC 43300 were used. Antibacterial assay of CuO nanoparticles showed antibacterial activity toward the pathogenic bacterial strains of E. coli by 5 mm and S. aureus by 5.5 mm for maximum zone of inhibition. In conclusion, this study presented simple, low expensive, eco-friendly and high productivity in the fabrication of CuO nanoparticles. In addition, these metallic nanoparticles had antibacterial effect that could be usable in medicinal aspect for fighting against prominent pathogen bacteria such as E. coli ATCC 25922 and S. aureus ATCC 43300.

show abstract

Section: Antibacterial Activitymentioning

confidence: 99%

Effect of Incubation Time, CuSO4 and Glucose Concentrations on Biosynthesis of Copper Oxide (CuO) Nanoparticles with Rectangular Shape and Antibacterial Activity: Taguchi Method Approach

Rad¹,

Taran²,

Alavi³

2018

Nano BioMed ENG

View full text Add to dashboard Cite

show abstract

“…The synthesis or extraction of compounds such as nanoparticles with antimicrobial properties is important and has potentially promising applications in the fight against the increasing number of pathogens resistant to currently available antimicrobials. These pathogens pose a continuous threat to human and animal health (Usman et al, 2013& Kruk et al, 2015. This paper presents a systematic review of the literature on antimicrobial copper nanoparticles, their current applications and their potential use in the area of oral health, specifically in the field of endodontics.…”

Section: Introductionmentioning

confidence: 99%

Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review

Sánchez‐Sanhueza

Fuentes‐Rodríguez

Bello-Toledo

2016

Int. J. Odontostomat.

View full text Add to dashboard Cite

ABSTRACT:Copper was registered as the first solid antimicrobial material. Its availability makes it an important option as an antibacterial agent. At nanoparticle size it does not exceed 100 nm, allowing close interaction with microbial membranes, enhancing its effect even more. Copper generates toxic hydroxyl radicals that damage cell membranes of Gram-negative and Gram-positive bacteria, among the latter, Enterococcus faecalis, which are present in infected radicular canals. Synthesis of metal nanoparticles with antimicrobial properties has become a viable alternative and has promising applications in the fight against pathogenic microorganisms. Furthermore, the use of some polymers to stabilize nanoparticles increases their release time and may as well decrease the risk of bacterial recolonization and biofilm formation within the ducts, enhancing the antimicrobial properties of these compounds.The aim of this article is to conduct a systematic review of the literature on antimicrobial copper nanoparticles, their current applications and their potential use in the area of oral health, specifically in the field of endodontics.

show abstract

“…Because of the large number of NH 2 -and OH-in chitosans chemical structure, chitosan can be used as effective anchoring agent for metal nanoparticles (NPs). Cu NPs have pronounced bactericidal properties against various types of organisms [8]. The improved antimicrobial activity of Cu NPs as compared to copper salt is due to their unique property, i.e., large surface area to volume ratio [9].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of chitosan–copper nanocomposites and their fungicidal activity against two sclerotia-forming plant pathogenic fungi

et al. 2017

View full text Add to dashboard Cite

In this report, the metal-vapor synthesis (MVS) was used for the preparation of copper nanoparticles which was then used for the preparation of chitosan-copper nanocomposite. The antifungal activity of Cu@Chit NCs against two sclerotium-forming plant pathogenic fungi Sclerotium rolfsii (S. rolfsii) and Rhizoctonia solani (R. solani) AG-4 was evaluated in vitro and their effects on hyphal morphology, and sclerotia formation were observed for the first time. The NCs were prepared through impregnation of chitosan with colloid solution of copper nanoparticles in organic solvent (acetone or toluene). Transmission electron microscopy shows that the particles have predominantly spherical form, polydisperse character, the mean diameter about 2-3 nm and a rather uniform distribution in the chitosan matrice. Analysis of the small angle scattering curves suggests that the copper particles in the NCs with the size of B2 nm are mostly located in the chitosan pores with the same size. The effect of Cu@Chit NCs on fungal growth reveals some significant inhibitory activity against two tested fungi. The highest level of inhibition against S. rolfsii and R. solani AG-4 was observed using the high concentrations of Cu@Chit NC prepared using acetone as a solvent. A loss of the cytoplasm content, cytoplasmic coagulation, irregular shape of mycelia, or destruction in the hyphae was confirmed. The experiments demonstrate that the Cu@Chit NC synthesized via MVS using acetone was more effective than that of toluene in inhibiting fungal hyphae growth against R. solani AG-4 and S. rolfsii. The results show that the Cu@Chit NCs are fungicidal against both the tested fungus at high concentrations and the fungicidal or fungistatic activity is dependent on the tested fungus species.

show abstract

Synthesis and antimicrobial activity of monodisperse copper nanoparticles

Cited by 224 publications

References 54 publications

Effect of Incubation Time, CuSO4 and Glucose Concentrations on Biosynthesis of Copper Oxide (CuO) Nanoparticles with Rectangular Shape and Antibacterial Activity: Taguchi Method Approach

Effect of Incubation Time, CuSO4 and Glucose Concentrations on Biosynthesis of Copper Oxide (CuO) Nanoparticles with Rectangular Shape and Antibacterial Activity: Taguchi Method Approach

Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review

Synthesis and characterization of chitosan–copper nanocomposites and their fungicidal activity against two sclerotia-forming plant pathogenic fungi

Contact Info

Product

Resources

About