“…Likewise, nine substances 5, 6, 7, 10, 11, 15, 17, 19, and 28 were effective only in the scPTZ test. Derivatives 5,7,9,11,12,13,15,17,19, and 28 showed protection at the dose of 100 mg/kg after 4 h. It is a better protection at thse same time point than the result of ethosuximide, recognized as the model antiepileptic drug effective in the scPTZ test. Especially interesting seem to be compounds 11 and 12, which revealed activity at the dose of 100 mg/kg not only after 4 h, but also after 0.5 h. The other compounds have demonstrated protection at the dose of 300 mg/kg after 4 h (6 and 10), and 0.5 h (compound 9).…”