Synthesis and anticancer evaluation of novel acenaphtho [1,2-e]-1,2,4- triazine derivatives
Abstract:In this paper, we present the convenient syntheses of some new phenyl hydrazin derivatives 8 (a-h). For this purpose, condensation of thiosemicarbazide and acenaphtylene-9,10-quinone was performed to form acenaphtho[1,2-e]-1,2,4triazine-9(8H)-thiones. Afterwards, the subsequent reaction with benzyl chloride derivatives was subjected to hydrazine and, then, the reaction was proceeded with different benzaldehyde derivatives to achieve 9-(phenyl imino hydrazin)acenaphtho[1,2-e]-1,2,4-triazine derivatives (8a-h) i… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.