Synthesis and anticancer activities of proline-containing cyclic peptides and their linear analogs and congeners

Ghosh, Keshab Ch; Duttagupta, Indranil; Bose, Chandra; Banerjee, Priya R.; Gayen, Anuran K; Sinha, Surajit

doi:10.1080/00397911.2018.1550201

Cited by 3 publications

(1 citation statement)

References 34 publications

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“…The recent discovery of linear and cyclic peptides with novel chemical structural attributes in marine organisms [ 55 ] is of considerable significance. These peptides have exhibited strong ion channel-specific blocking potential along with other pathological and pharmacological prospects [ 56 , 57 , 58 , 59 ].…”

Section: Marine Bioactive Peptides (Mbaps)mentioning

confidence: 99%

Therapeutic Potential of Marine Bioactive Peptides against Human Immunodeficiency Virus: Recent Evidence, Challenges, and Future Trends

et al. 2022

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Acquired immunodeficiency syndrome (AIDS) is a chronic and potentially fatal ailment caused by the human immunodeficiency virus (HIV) and remains a major health problem worldwide. In recent years, the research focus has shifted to a greater emphasis on complementing treatment regimens involving conventional antiretroviral (ARV) drug therapies with novel lead structures isolated from various marine organisms that have the potential to be utilized as therapeutics for the management of HIV-AIDS. The present review summarizes the recent developments regarding bioactive peptides sourced from various marine organisms. This includes a discussion encompassing the potential of these novel marine bioactive peptides with regard to antiretroviral activities against HIV, preparation, purification, and processing techniques, in addition to insight into the future trends with an emphasis on the potential of exploration and evaluation of novel peptides to be developed into effective antiretroviral drugs.

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