Synthesis and Antibacterial Screening of N‐[Naphtho[1,2‐b]pyrano [3,4‐d]thiazol‐8‐yl]spiroindoloazetidin‐2‐ones/thiazolidin‐4‐ones.

Abstract

1,2-b]pyrano[3,4-d]thiazol-8-yl]spiroindoloazetidin-2-ones/thiazolidin-4-ones.-All products possess considerable antibacterial activity. -(SURYAVANSHI, J. P.; PAI*, N. R.; Indian J.

(Z)-2-(5-Chloro-2-oxoindolin-3-ylidene)-N-methylhydrazinecarbothioamide

“…Biological properties of isatin and its derivatives include a range of actions in the brain, offer protection against bacterial (Suryavanshi & Pai, 2006) and fungal infections and possess anticonvulsant, anti-HIV (Pandeya et al, 1999), anti-depressant and anti-inflammatory activities (Bhandari et al, 2008). Recently, we reported the crystal structure of (Z)-2-(5-chloro-2-oxoindolin-3-ylidene)-N-methylhydrazinecarbothioamide (Qasem Ali et al, 2012).…”

“…For various biological activities of Schiff bases, see: Bhandari et al (2008); Bhardwaj et al (2010); Pandeya et al (1999); Sridhar et al (2002); Suryavanshi & Pai (2006). For cytotoxic and anticancer activities of isatin and its derivatives, see: Vine et al (2009).…”

(Z)-2-(2-Oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide

“…For various biological activities of Schiff bases, see: Bhandari et al (2008); Bhardwaj et al (2010); Pandeya et al (1999); Sridhar et al (2002); Suryavanshi & Pai (2006). For the cytotoxic and anticancer activities of isatin and its derivatives, see: Vine et al (2009).…”

“…The biological properties of isatin and its derivatives include a range of actions in the brain, offer protection against bacterial (Suryavanshi & Pai, 2006) and fungal infections and possess anticonvulsant, anti-HIV (Pandeya et al, 1999), antidepressant and anti-inflammatory activities (Bhandari et al, 2008). Recently, we reported the crystal structure of (Z)-2-(5-chloro-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (Qasem Ali et al, 2011a).…”

Synthesis and antimicrobial activities of 2-azetidinyl-4-quinazolinone derivatives of diclofenac analogue

“…b-Lactam (4-membered cyclic amide) ring structure constitutes the dominant class of agents currently employed for the chemotherapy of bacterial infections. Various 2-azetidinones have been reported to possess antibacterial (Halve et al, 2006;Suryavanshi and Pai, 2006), antifungal (Havaldar and Khatri, 2006;Panwar et al, 2006), anti-inflammatory (Gurupadayya et al, 2008), anthelminthic (Srivastava et al, 2004), antiviral (Pandey et al, 2005) and anticonvulsant (Rajasekaran and Murugesan, 2005) activities.…”