Synthesis and anti-herpes simplex viral activity of monoglycosyl diglycerides

Probiotic microorganisms and antiviral plants reduce mortality and prevalence of WSSV in shrimp (Litopenaeus vannamei) cultured under laboratory conditions

“…3). Extracts of some medicinal plants such as Palo María ( C. inphyllum ), Purple Basil ( O. basilicum ) and Gooseberry ( P. acidus ) have shown to have antiviral activity against the yellow head virus in P. monodon (Direksaburakom et al 1996; Janwitayanuchit et al 2003). The fact that powdered plants were more effective in protecting shrimp against WSSV than aqueous PEs might indicate that the active compound(s) might not be soluble in water or they may be thermo labile and become degraded during preparation of the extract.…”

“…Medicinal plant extracts (PEs) have been utilized for the control of viral and bacterial diseases in salmonids, such as Oncorhynchus masou , in which Guava ( Psidium guajava ) has demonstrated to have antiviral activity against the virus of infectious haematopoietic necrosis (Direksaburakom, Herunsalee & Rongkumnardwong 1996; Direkbusarakom 2004). In shrimp culture, the extracts of some medicinal plants, such as Palo María ( Callophyllum inphyllum ), Purple Basil ( Ocimum basilicum ) and Gooseberry ( Phyllanthus acidus ), have been shown to have antiviral activity against the virus of the yellow head in the shrimp Penaeus monodon (Direksaburakom et al 1996; Janwitayanuchit, Suwanborirux, Patarapanich, Pummangura, Lipipun & Vilaivan 2003).…”

Total Synthesis and Structure-Activity Relationship of Glycoglycerolipids from Marine Organisms

“…The synthesis of 1,2-diacyl-3- O -β- d -glucopyranosyl- sn -glycerols and corresponding α-glycoside are reported respectively as examples to introduce their work (Scheme 1 and Scheme 2). Generally, the Koenigs-Knorr method using acyl glycosyl halide as glycosyl donor and silver oxide/iodine as the catalyst was adopted to construct β- d -glycoside in synthesis of the glycoglycerolipids [58,63,64]. However, intramolecular migration usually occurred when 1,2- O -isopropylidene- sn -glycerol was used as the acceptor under Koenigs-Knorr method [65].…”

Herbs for Treating Herpes Zoster Infections

“…Monoglycosylated diglycerides from this herb have shown anti-HSV-1 activity in vitro. 8 An extract of Clinacanthus was also found to have immunomodulating properties in vitro. 9 Licorice (Glycyrrhiza glabra) root and its relative Chinese licorice (Glycyrrhiza uralensis) root both contain the triterpenoid saponin glycyrrhizin.…”