Synthesis and aggregation properties of novel amino acetals with the calix[4]resorcinol platform

Abstract

Reactions of calixarenes with methylaminoacetaldehyde dimethyl acetal and formalin gave Mannich bases with the calixarene platform. It was found by dielcometric titration that calix[4]resorcinols with acetal groups in the aminomethyl fragment form head to head supra molecular aggregates in chloroform at low concentrations.

Solubilities of C-Tetraalkylcalix[4]resorcinarenes in SCCO2: Experimental Measurements, Characterization, and Correlation

“…Resorcinarenes are cyclic compounds belonging to calixarenes group and are produced by a polycondensation reaction between resorcinol and acetaldehyde. − The presence of two hydroxide groups in the benzene rings, forming the macrocycle, determines their relatively easy participation in a large number of chemical interactions. In the past decade resorcinol based calixarenes, and especially calix[4]­resorcinarenes, the smallest members of the resorcinarene family, have proved to be valuable for many applications in chemistry, biology, and medicine. − …”