Synthesis and aggregation properties in water solution of comblike methacrylic polymers with oligo(propylene glycol)‐block‐oligo(ethylene glycol) as side chains

Effects of graft length and density of well‐defined graft polymers on the thermoresponsive behavior and self‐assembly morphology

“…This result agreed quite well with Huang's report, indicating that higher graft density would form irregular morphology and make the size distribution asymmetric because of steric hindrance between graft side chains . Paris and Garrido also found that the molecular weight and PDI had a notable effect on the diameter and size distribution of the formed micelles …”

Smart poly(oligo(propylene glycol) methacrylate) hydrogel prepared by gamma radiation

“…The LCST of the copolymers was varied by changing the ratios of the co-monomers. By increasing the ratio of the hydrophilic OEGMA and DMAEMA to hydrophobic OPGMA, the thermal transition temperature was increased significantly, leading to OPGMA copolymers with LCSTs close to body temperature and applicable for the delivery of drugs and cells [23,24,30]. Thermoresponsive water-soluble PEGMEMA-OPGMA-EGDMA co-polymers have also been prepared via a facile one-step deactivation enhanced ATRP copolymerisation of monofunctional and multifunctional vinyl monomers; these terpolymers have demonstrated LCST behaviour and photocrosslinkable properties [25].…”

“…Thus, thermoresponsive polymers based on acrylate or methacrylate with oligo(ethylene glycol) (OEG) side chains have been proposed as thermoresponsive poly(ethylene glycol) (PEG) analogues for biomedical applications [6]. Oligo(ethylene glycol) (meth)acrylates have been widely used in a number of thermoresponsive materials [3,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22], while oligo(propylene glycol) methacrylates have been less exploited on account of their poor amphiphilic character [23][24][25][26]; nevertheless, OPGMA monomers have been used in biomaterials, coatings and nail polish, and photosensitive materials [27,28]. In general, the greater hydrophobicity of PPGs induces much lower LCST temperatures than in the case of PEGs.…”

Tuning the thermoresponsive properties of poly(oligo(propylene glycol) methacrylate) hydrogels via gradient copolymerization with 2-hydroxyethyl methacrylate

“…The LCST of the copolymers was varied by changing the ratios of the comonomers. By increasing the ratio of the hydrophilic OEGMA and DMAEMA to hydrophobic OPGMA, the thermal transition temperature was increased significantly, leading to OPGMA copolymers with LCSTs close to body temperature and applicable for the delivery of drugs and cells [37][38]42]. Thermoresponsive water-soluble poly(ethylene glycol) methyl ether methacrylate-poly(propylene glycol) methacrylate-ethylene glycol dimethacrylate (PEGMEMA-PPGMA-EGDMA) copolymers have also been prepared via a facile one-step deactivation enhanced ATRP copolymerization of monofunctional and multifunctional vinyl monomers [44].…”

“…Thus, thermoresponsive polymers based on acrylate or methacrylate with oligo(alkylene glycol) (OAG) side chains have been proposed as thermoresponsive PAG analogues for biomedical applications [18]. Oligo(ethylene glycol) (meth)acrylates have been more frequently used [1,5,18,[27][28][29][30][31][32][33][34][35][36] in contrast to oligo (propylene glycol) methacrylates which have been less exploited on account of their poor amphiphilic character [37][38][39]; nevertheless, OPGMA functionalized monomers have been used in biomaterials, coatings and nail polish, and photosensitive materials [40,41]. In general, the greater hydrophobicity of PPGs induces much lower LCST temperatures than in the case of PEGs.…”