Syntheses of Enaminone-Based Heterocyclic Compounds and Study their Biological Activity

Abstract

We herein reported the utility of 3-(3-(dimethylamino)acryloyl)-2H-chromen-2-one (2), as a versatile precursor for the synthesis of some new azole systems of possible biological activities. The structure of the newly synthesized compounds has been confirmed by IR, 1 H NMR, mass spectral and elemental analysis. Furthermore, some selected compounds were screened in vitro for their anti-microbial activities. The results declared that most of the synthesized compounds have high anti-microbial activity.

Phytochemical Screening of Caralluma lasiantha Isolation of C21 Pregnane Steroid

“…It was also concluded that the present C21 steroid can be helpful as a marker for Caralluma genus. As different moieties and functional groups present on synthetic / natural molecules direct their pharmacological activities [30][31][32][33][34][35] , structure activity relationship between such activities and this isolated molecule can be further studied.…”