Syntheses, Crystal Structure, and Nuclease Activity of Oxalato-Bridged Dicopper(II) Complexes with Planar N-Donor Heterocyclic Bases

Metal-assisted light-induced DNA cleavage activity of 2-(methylthio)phenylsalicylaldimine Schiff base copper(II) complexes having planar heterocyclic bases

“…A Cu:phen ratio of 1:2 is required for its efficient cleavage activity. While several types of copper complexes cleaving DNA in the absence or presence of a reducing agent are recently reported [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32], examples of copper complexes showing photoinduced DNA cleavage are generally limited to the porphyrin species [9]. Among non-porphyrinic copper(II) complexes, Zaleski and coworkers [33] have recently reported a binary complex, viz.…”

Cleavage of double-strand DNA by linear and triangular trinuclear copper complexes

“…Among all of the reported metal complexes, the most attractive class is copper(II) complexes, which have been extensively applied as catalysts due to their efficient cleavage of nucleic acids last two decades [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. In view of a number of nucleases with two or three metal ions in their catalytic centre [28], considerable efforts have been made to develop multiple metal models [29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44].…”

Synthesis, crystal structure, and DNA interaction studies of a mixed-ligand copper(II) complex of 1,10-phenanthroline and a Schiff base derived from isoleucine

“…Copper is a bioessential element and its complexes have been found to have potential for the treatment of cancers and many other diseases [4]. It was reported that copper(II) complexes can interact noncovalently with nucleic acids by intercalation when they incorporate planar fused aromatic ring systems [5]. Hence, complexes with 1,10-phenanthroline and its derivatives have drawn much attention due to their high nucleolytic efficiency [6].…”