“…VAMP-8, one of the SNARE types localized to the endosomes, had been shown to play important roles, from homotypic fusion of early and late endosomes (15,18), exocytosis of vesicles (14,19,28,29), cytokinesis (30), to its role in phagocytosis modulation (our current findings). VAMP-8 forms complexes with Syn-7, Syn-8, and Vti1b, which mediates homotypic fusion of early and late endosomes (15,17,18).…”