Synopsis of the Organ Anatomy

Komárek, Vladimı́r; Gembardt, C; Krinke, A.; MAHROUS, T; Schaetti, P.

doi:10.1016/b978-012426400-7/50054-6

Cited by 3 publications

(5 citation statements)

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“…The acinar cells of the mandibular gland include a mucinous secretion, whereas the cells lining the excretory ducts present serous granules (Hofstetter et al., 2006). Other reports are suggesting that the mandibular gland has both serous and mucous acinar cells (Komarek et al., 2000). Interestingly, mucus‐secreting cells were identified in 100% of rat males, but only 28.5% in sexually mature female rats, suggesting sexual dimorphism (Hatakeyama et al., 1987).…”

Section: Discussionmentioning

confidence: 96%

“…The acinar cells of the mandibular gland include a mucinous secretion, whereas the cells lining the excretory ducts present serous granules (Hofstetter et al, 2006). Other reports are suggesting that the mandibular gland has both serous and mucous acinar cells (Komarek et al, 2000).…”

Section: Discussionmentioning

confidence: 99%

“…In rats, the parotid gland extends ventrorostrally, starting behind the ear and ending on the ventrolateral side of the neck. It includes three to four individual lobes that consist of serous adenomeres, the gland producing saliva with a protein concentration of nearly 2% (Hofstetter et al., 2006; Komarek et al., 2000). The mandibular (or submaxillary) gland is located caudal to the mandibular angle and extends caudally up to manubrium.…”

Section: Discussionmentioning

confidence: 99%

“…The first includes the minor sublingual, the palatine, the buccal and the lingual glands, whereas the greater ones are represented by the parotid, mandibular and sublingual glands. Basically, the glands are made of acinar cells and excretory ducts (Komarek et al., 2000). In rats, the parotid gland extends ventrorostrally, starting behind the ear and ending on the ventrolateral side of the neck.…”

Section: Discussionmentioning

confidence: 99%

“…Serous acini surface (μm However, the sublingual gland is tightly attached to the mandibular one (Komarek et al, 2000), and are smaller rounded structure situated towards the rostral edge of the mandibular glands, in some circumstances embedded partially in them (Hofstetter et al, 2006). With age, in male rats, the ratio of the excretory ducts versus the acini in the gland increases, and the ductal epithelium undergo frequently squamous metaplasia (Mintz & Mooradian, 1987).…”

Section: Mucous Acini Surface (μM 2 )mentioning

confidence: 99%

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Microanatomical, histochemical and morphometric features of the major and selected minor salivary glands in laboratory Wistar rat

Adrian Florin,

Maria‐Catalina,

Viorel

et al. 2023

Anat Histol Embryol

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The major and minor salivary glands are responsible for saliva production, a fluid drained in the oral cavity that will be involved in several functions at this level. The present study aimed to compare the microanatomy of the major (parotid, mandibular, sublingual) and minor salivary glands (von Ebner's and Weber's) of the Wistar rat, from a histological, histochemical and morphometrically point of view. Predominantly serous glands (parotid, mandibular and von Ebner's) showed differences in the secretion composition on both PAS and alcian blue reactions. The same observations were identified also for the mostly mucous salivary glands (sublingual and Weber). In terms of surface dimensions, the measurements suggested that the mucous acini have a greater surface compared with the serous ones, and, at the same time, a better‐represented polymorphism. In conclusion, the major and minor salivary glands in Wistar rats, a commonly used species in experimental procedures, showed similarities with other species including humans, but some structural traits are breed‐specific, this finding is very important for an extensive understanding of the morphophysiology of the salivary glands.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Mucous Acini Surface (μM 2 )mentioning

confidence: 99%

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Microanatomical, histochemical and morphometric features of the major and selected minor salivary glands in laboratory Wistar rat

Adrian Florin,

Maria‐Catalina,

Viorel

et al. 2023

Anat Histol Embryol

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Structure and Function of Mammal Skin

Paterson¹

2006

Skin Diseases of Exotic Pets

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Preventive and therapeutic effects of SkQ1-containing Visomitin eye drops against light-induced retinal degeneration

Novikova

Gancharova

Eichler

et al. 2014

Biochemistry Moscow

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The human retina is constantly affected by light of varying intensity, this being especially true for photoreceptor cells and retinal pigment epithelium. Traditionally, photoinduced damages of the retina are induced by visible light of high intensity in albino rats using the LIRD (light-induced retinal degeneration) model. This model allows study of pathological processes in the retina and the search for retinoprotectors preventing retinal photodamage. In addition, the etiology and mechanisms of retina damage in the LIRD model have much in common with the mechanisms of the development of age-related retinal disorders, in particular, with age-related macular degeneration (AMD). We have studied preventive and therapeutic effects of Visomitin eye drops (based on the mitochondria-targeted antioxidant SkQ1) on albino rat retinas damaged by bright light. In the first series of experiments, rats receiving Visomitin for two weeks prior to illumination demonstrated significantly less expressed atrophic and degenerative changes in the retina compared to animals receiving similar drops with no SkQ1. In the second series, the illuminated rats were treated for two weeks with Visomitin or similar drops without SkQ1. The damaged retinas of the experimental animals were repaired much more effectively than those of the control animals. Therefore, we conclude that Visomitin SkQ1-containing eye drops have pronounced preventive and therapeutic effects on the photodamaged retina and might be recommended as a photoprotector and a pharmaceutical preparation for the treatment of AMD in combination with conventional medicines.

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Synopsis of the Organ Anatomy

Cited by 3 publications

References 0 publications

Microanatomical, histochemical and morphometric features of the major and selected minor salivary glands in laboratory Wistar rat

Microanatomical, histochemical and morphometric features of the major and selected minor salivary glands in laboratory Wistar rat

Structure and Function of Mammal Skin

Preventive and therapeutic effects of SkQ1-containing Visomitin eye drops against light-induced retinal degeneration

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