Synergizing Proteolysis-Targeting Chimeras and Nanoscale Exosome-Based Delivery Mechanisms for HIV and Antiviral Therapeutics
Nobendu Mukerjee,
Swastika Maitra,
Arabinda Ghosh
et al.
Abstract:The global fight against Human Immunodeficiency Virus
(HIV) and
related viral infections stands at a pivotal juncture, demanding groundbreaking
therapeutic strategies. Facing the challenges of existing antiviral
treatments, such as viral resistance and nonspecific actions, this
paper unveils a transformative approach. We introduce an innovative
synergy between proteolysis-targeting chimeras (PROTACs) and exosome-based
delivery mechanisms, heralding an innovative era in combating HIV
and similar viral diseases.… Show more
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