Synergistic modulation of chitosan on the mechanical and disintegration properties of pre-gelatinized waxy corn starch orally disintegrating film

Li, Yuhang; Ma, Wentao; Cui, Bo; Yuan, Chao; Zhao, Meng

doi:10.1016/j.fbio.2023.103317

Cited by 2 publications

(1 citation statement)

References 57 publications

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“…Li et al [77] produced oral disintegration films based on pre-gelatinized waxy corn starch and different concentrations of chitosan (10 to 30%) and reported that compared to the control oral disintegration film (pre-gelatinized waxy corn starch), the tensile strength and elongation of the films increased by up to 20% (w/w), presenting values between 2 to 5 MPa and 20 to 40% for TS and E, respectively. The authors attributed this effect to the formation of more uniform chains after the addition of chitosan in the oral disintegration films.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

Oral Films Printed with Green Propolis Ethanolic Extract

Remedio,

Garcia,

Rochetti

et al. 2024

Polymers

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Oral film (OF) research has intensified due to the effortless administration and advantages related to absorption in systemic circulation. Chitosan is one of the polymers widely used in the production of OFs; however, studies evaluating the maintenance of the active principles’ activity are incipient. Propolis has been widely used as an active compound due to its different actions. Printing techniques to incorporate propolis in OFs prove to be efficient. The objective of the present study is to develop and characterize oral films based on chitosan and propolis using printing techniques and to evaluate the main activities of the extract incorporated into the polymeric matrix. The OFs were characterized in relation to the structure using scanning and atomic force electron microscopy; the mechanical properties, disintegration time, wettability, and stability of antioxidant activity were evaluated. The ethanolic extract of green propolis (GPEE) concentration influenced the properties of the OFs. The stability (phenolic compounds and antioxidant activity) was reduced in the first 20 days, and after this period, it remained constant.

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Section: Mechanical Propertiesmentioning

confidence: 99%