Synergistic function of Au NPs/GeO2 nanozymes with enhanced peroxidase-like activity and SERS effect to detect choline iodide

Tang, Ruyi; Xia, Xuemin; Zhang, Xia; Jiang, Huan; Zhang, Peilei; Zhang, Yujin; Tang, Yanxue; Zhou, Yi

doi:10.1016/j.saa.2021.120467

Cited by 15 publications

(1 citation statement)

References 31 publications

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“…It has shown that the interaction between two or more components allows nano-enzymes to exhibit novel properties and their enzyme-like activity can be regulated by changing the ratio of different components in the nanomaterials, showing surprising synergistic effects in the field of biosensors and immunoassays. For example, Zhou et al found that Au NP/GeO 2 nano-enzymes exhibited stronger peroxidase-like activity than single Au NPs or GeO 2 [ 57 ]. Zhong et al synthesized a novel H 2 O 2 dual sensor constructed from TMB-Fe 3 O 4 @Au NPs by combining colorimetry and surface-enhanced Raman spectroscopy [ 58 ].…”

Section: Sensing Strategy Based On the Activity Of Au Np-like Enzymesmentioning

confidence: 99%

Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles

Cui

Zhao

2023

Biosensors

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The colorimetric signal readout method is widely used in visualized analyses for its advantages, including visualization of test results, simple and fast operations, low detection cost and fast response time. Gold nanoparticles (Au NPs), which not only exhibit enzyme-like activity but also have the advantages of tunable localized surface plasmon resonance (LSPR), high stability, good biocompatibility and easily modified properties, provide excellent platforms for the construction of colorimetric sensors. They are widely used in environmental monitoring, biomedicine, the food industry and other fields. This review focuses on the chromogenic mechanisms of colorimetric sensors based on Au NPs adopting two different sensing strategies and summarizes significant advances in Au NP-based colorimetric sensing with enzyme-like activity and tunable LSPR characteristics. In addition, the sensing strategies based on the LSPR properties of Au NPs are classified into four modulation methods: aggregation, surface modification, deposition and etching, and the current status of visual detection of various analytes is discussed. Finally, the review further discusses the limitations of current Au NP-based detection strategies and the promising prospects of Au NPs as colorimetric sensors, guiding the design of novel colorimetric sensors.

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Section: Sensing Strategy Based On the Activity Of Au Np-like Enzymesmentioning

confidence: 99%