Synergistic effects of Fe-Se dual single-atom sites for boosting electrochemical nonenzymatic H2O2 sensing

Selenium-doped carbon materials: synthesis and applications for sustainable technologies

“…Exploiting this approach, many different Se/Fe/N ternary-doped carbon catalysts have been produced. 69–71 A Fe/Se dual-atomic-site catalyst was prepared from a mixture of melamine, l -alanine, SeO 2 , and iron trichloride via pyrolysis at 900 °C (Fig. 13).…”

“…Dong and co-workers studied Se-containing metal-free and metal-doped single and dual-atomic-site catalysts for nonenzymatic sensing of H 2 O 2 . 47,70 Significantly, the designed sensors were successfully utilized for H 2 O 2 detection in disinfectant and urine samples. For example, a ZIF-8 derived Se/N co-doped material with single Se sites exhibited high electrocatalytic activity for H 2 O 2 reduction and thus was applied for its detection in a wide range from 0.04 to 11.1 mM, with a low detection limit (0.018 mM) and high sensitivity of ca.…”

“…47 This same research group also synthesized a dual-site Fe–Se catalyst based on an N-doped carbon and studied it in nonenzymatic detection of H 2 O 2 . 70 The simultaneous doping of Se and Fe enhanced the electrocatalytic activity for peroxide reduction, allowing outstanding sensing properties. Thanks to the synergistic effect of Fe/Se dual doping that improved the electron transfer rate, the hydrogen peroxide could be detected in a wide linear range (0.02–13 mM) with a high sensitivity of 1508.6 μA mM −1 cm −2 and an 11.5 μM detection limit.…”

Single-Atom Ru Biomimetic Nanozyme for the Electrochemical Sensing of Hydrogen Peroxide

“…1−3 Notably, excessive and high concentrations of H 2 O 2 could exert adverse effects on human health, and the change in H 2 O 2 concentration in living systems is associated with various cellular functions. 4,5 Hence, developing a straightforward and sensitive approach for fast and precise monitoring of H 2 O 2 levels in different media is of great significance. The electrochemical sensor is a reliable approach for detecting and quantifying H 2 O 2 with the merits of low cost, quick response, and high sensitivity.…”

“…Hydrogen peroxide (H 2 O 2 ), the most essential molecule, plays a crucial role in biological and chemical engineering, and environmental applications. − Notably, excessive and high concentrations of H 2 O 2 could exert adverse effects on human health, and the change in H 2 O 2 concentration in living systems is associated with various cellular functions. , Hence, developing a straightforward and sensitive approach for fast and precise monitoring of H 2 O 2 levels in different media is of great significance. The electrochemical sensor is a reliable approach for detecting and quantifying H 2 O 2 with the merits of low cost, quick response, and high sensitivity. − It is worth noting that electrochemical sensors based on nanomaterials that feature biomimetic enzyme-like activity toward H 2 O 2 are more favored due to the complicated electrode modification process of natural enzyme-based sensors and the susceptible inactivation of natural enzymes affected by temperature, humidity, and pH .…”