Abstract:Background
Chronic neuro‐inflammation leading to excessive neuronal damages predates the presence of clinical manifestations of Alzheimer’s disease (AD) by many years. Due to the complex pathogenesis of AD, a multi‐target regimen using a combination therapy is proposed to be essential to the effectiveness of AD therapy.
Method
An innovative combination therapy using a newly developed multi‐functional Aβ antibody (NP106) and a novel curcumin derivative (TML‐6) was applied to treat APP/PS1 mice. To investigate w… Show more
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