Synergistic Effect of Brevetoxin BTX-3 and Ciguatoxin CTX3C in Human Voltage-Gated Nav1.6 Sodium Channels
Sandra Raposo-Garcia,
Celia Costas,
M. Carmen Louzao
et al.
Abstract:Emerging
marine biotoxins such as ciguatoxins and brevetoxins have
been widely and independently studied as food pollutants. Their maximum
levels in food components were set without considering their possible
synergistic effects as consequence of their coexistence in seafood
and their action at the same cellular target. The absolute lack of
data and regulations of the possible combined effects that both marine
biotoxins may have raised the need to analyze their direct in vitro effects using electrophysiology t… Show more
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