Synergistic Antineoplastic and Immunomodulatory Effects of Hesperidin in Ehrlich Ascites Carcinoma Tumor Model Treated with Cisplatin
Abstract:Despite substantial advancements in cancer research in recent years, the treatment of cancer remains fraught with difficulties. Cisplatin is a strong chemotherapeutic drug used to treat a variety of cancers, but its efficacy is limited by drug resistance and toxic effects on non-tumor tissues. The flavonoid hesperidin was reviewed to have anticancer properties. In the present study, a tumor model was established, cisplatin plus hesperidin synergism was conducted, antineoplastic and immunomodulatory effects wer… Show more
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