Synergistic antibacterial activity of EGCGcombined with imipenem against planktonic Carbapenem-resistant Klebsiella pneumoniae and the evaluation of independent antibiofilm activity of EGCG
Longtao Zhang,
Anran Zhang,
Qianqian Chen
et al.
Abstract:Purpose
To explore the synergistic antibacterial activity of EGCG combined with IMP against planktonic CRKP and evaluate the independent antibiofilm activity of EGCG.
Methods
Broth microdilution method was determined the MIC of EGCG. synergistic antibacterial activity between EGCG and IMP against planktonic CRKP was assessed by the FIC index. MBIC and MBRC were determined to describe the antibiofilm activity of EGCG using a microtiter plate assay. PCR was carried out to detect the presences and the relative … Show more
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