Synergic Effect of Trimebutine Combined with Mosapride on Gastrointestinal Dysfunction and Visceral Pain Induced in Stress Models

Abstract

Abstractgastric neurosis, gastroptosis, or refl ux esophagitis (Wingate et al., 2002). Even though there have been great advances in our understanding of the neurohumoral mechanisms controlling gastrointestinal motility in health and disease, the underlying pathogenesis of this condition is not fully understood, therefore, various drugs are used in the treatment of gastrointestinal motility disorders.A gastroprokinetic agent is a type of drug which enhances gastrointestinal motility by increasing the frequency of con-