Synergestic effect of gallic acid lipid nanoparticles to improve the physiochemical property and cellular uptake against MDA MB 231 Cancer cell line: Apoptosis, signaling pathway and cytotoxicity
Abstract:Introduction: Gallic acid (GA), a phenolic molecule that occurs naturally, has been shown to have anti-tumor properties for a number of cancer types. The effect of GA on breast tumor cells MDA-MB-231 Triple Negative was examine in the current study. Methods: Techniques were utilised for cell cycle analysis, GSH concentration, Annexin V assay, light and fluorescence microscopy, restriction of cell growth (MTT assay), preparation, characterisation, and measurement of the mitochondrial membrane potential. Results… Show more
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