Syncytiotrophoblast extracellular microvesicles in preeclampsia

Abstract

Attempts at predicting and diagnosing preeclampsia has so far been unsuccessful, with most studies investigating circulating free proteins or microRNAs. There is a need for improved noninvasive diagnosis and monitoring for preeclampsia outside the current clinical parameters. Such a biomarker would allow for preventative treatments to keep both the mother and fetus safe. It is well known that placental syncytiotrophoblasts at the maternal-fetal