Synchronous primary diffuse large B-cell lymphoma and papillary thyroid carcinoma: a case report highlighting “Lymphoma first approach”

Abstract

Papillary thyroid carcinoma (PTC) is the most common type of all thyroid carcinomas and accounts for up to 90% of all thyroid malignancies. It is the most indolent form of the disease and has an excellent prognosis. On the other hand, Primary thyroid lymphoma (PTL) is a rare entity accounting for only about 1% to 5% of all thyroid malignancies and only 2% of extranodal lymphomas. Synchronous PTC and PTL is a very rare condition and only a few cases have been reported in the literature up till now. We report one such case in a 52-year-old lady who was referred to us with goiter and progressively increasing difficulty in breathing. Keywords: Synchronous thyroid malignancies, Papillary thyroid carcinoma, Lymphoma Continuous...

Lymphoma and Differentiated Thyroid Cancer: A Case Series

“…The synchronous occurrence of lymphoma and DTC is both a diagnostic and therapeutic challenge. The importance of the lymphoma-first approach is highlighted by Dhanani et al and Popivanov et al [ 9 , 10 ]. According to them, PTC is the most idle form of thyroid cancer, and enlarged cervical lymphadenopathy secondary to lymphoma will disappear or regress after the treatment of lymphoma, thus making surgery for PTC much easier with fewer complications.…”

Coexistence of primary thyroid diffuse large B cell lymphoma and papillary thyroid carcinoma in a patient with Hashimoto’s thyroiditis: a case report and literature review

“…The most common clinical manifestation is a rapidly growing neck mass and is reported in 88% of cases, most commonly in those with DLBCL ( 8 , 12 ). To the best of our knowledge, the coexistence of thyroid DLBCL and PTC is very rare, and only a handful of cases have been previously reported in the literature ( 13 – 18 ). A comparison of findings between the current and previously reported cases is depicted in Table 1 .…”