Synchronous primary carcinomas of the bladder and prostate

Lee, Sheng-Hui; Chang, Phei‐Lang; Chen, Shaoming; Sun, Guang‐Huan; Chen, Chien‐Lun; Shen, B.-Y.; Wu, Yao-Yu; Tsui, Ke‐Hung

doi:10.1111/j.1745-7262.2006.00129.x

Cited by 41 publications

(39 citation statements)

References 10 publications

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“…In this study, we found that the frequency of incidental PCa in China was 3.3%, similar to the frequency in Lee et al [10] and Yumura et al [7] studies (4% and 5.1%, respec tively), but was much lower than the frequency in other series of RCP cases (14% to 60%) [19] and the ageadjusted frequency of autopsy-detected PCa in China [4].…”

Section: Discussionsupporting

confidence: 45%

“…Of these npg patients, three had carcinoma in situ (CIS) involving the pro s tatic urethra and six had TCC involving the prostate glands/parenchyma. Our literature review identified eight articles from Korea, Japan, Iran, India, Taiwan, China and mainland China that we believe could represent the whole Asian population [7][8][9][10][11][12][13][14]. We combined our data with the data from the reviewed literature for analysis.…”

Section: Resultsmentioning

confidence: 99%

“…This could also partially explain why the incidence rate in our study is lower than that in other studies. Lee et al [10] 248 63 5 10 (4) 2 India Desai et al [12] 44 54.7 NA 3 (6.8) NA Japan Yumura et al [7] 59 N/A NA 3 (5.1) NA Mainland China Xia [11] 22 67.1 4 3 (13.6) 0…”

Section: Discussionmentioning

confidence: 99%

“…Liu et al [14] Lee et al [10] 248 (124) 10 (4) 0 0 Mainland China Xia [11] 22 (13) npg Although PSA is commonly used to screen for PCa, we did not find any difference in the PSA levels between patients with and without incidental PCa in the specimens, a result that has also been shown in several other studies [20,24,25]. We attributed this mainly to the low tumor volume and low Gleason score of incidentally detected PCa because in most cases of PCa, serum PSA levels correlate well with tumor volume and Gleason score [26,27].…”

Section: Mainlan Chinamentioning

confidence: 99%

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Prevalence of incidental prostate cancer in patients undergoing radical cystoprostatectomy: data from China and other Asian countries

Zhu¹,

Ye²,

Yao³

et al. 2008

Asian J Androl

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The purpose of this study is to investigate the frequency of prostate cancer (Pca) discovered incidentally in radical cystoprostatectomy specimens in Asia and to determine the feasibility of prostate-sparing cystectomy (PSC) for Asian patients. Ninety-two male bladder cancer patients who underwent radical cystoprostatectomy at our center between January 2003 and January 2008 were included in this study. The mean age of patients was 67.1 years (range: 32-75 years). Prostate-specific antigen (PSA) levels and digital rectal examination (DRE) results before surgery were obtained retrospectively. Prostates of all patients were embedded and sectioned at 5-mm intervals. The same pathologist examined the prostatic tissues from radical cystoprostatectomy specimens. Finally, a structured literature review was performed using MEDLINE and PUBMED to estimate the occurrence of incidental Pca in Asia. Of the 92 patients, 3 (3.3%) were found to have Pca; in one out of three (33.3%) patients the disease was clinically significant due to a Gleason grade 4 carcinoma. Eight articles were included in our review. The overall incidence of Pca discovered incidentally in radical cystoprostatectomy specimens in Asia was 9.9% (64/642). When age was restricted to < 60 years, only 7 out of 222 (3.2%) patients were found to have synchronous Pca, and none of the cases was clinically significant. The occurrence of Pca in radical cystoprostatectomy specimens in Asia is much lower than that in Western countries. PSC might be feasible for Asian patients under a strict preoperative selection.

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Section: Discussionsupporting

confidence: 45%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Mainlan Chinamentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of incidental prostate cancer in patients undergoing radical cystoprostatectomy: data from China and other Asian countries

Zhu¹,

Ye²,

Yao³

et al. 2008

Asian J Androl

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“…Incidental prostate carcinoma rates detected in cases having undergone RCP due to bladder tumor vary between 4% and 60% (Table 2) (2,6,(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22). One of the reasons for these various rates has been linked to the use of section intervals in different widths.…”

Section: Discussionmentioning

confidence: 99%

Incidental Prostate Cancer Frequency and Features of Patients Undergoing Radical Cystoprostatectomy

Balci¹,

Onuk²,

Hazar³

et al. 2016

JAREM

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Objective: Prostate cancer (PC) is one of the major health problems among males. Pathology specimens of patients with incidental PC who underwent radical cystoprostatectomy (RCP) have been reported to be 17-70% in different series. In this study, we aimed to determine the frequencies and features of incidental PC in patients who underwent RCP.Methods: In our study, 142 patients who underwent RCP were retrospectively evaluated between 1999 and 2015. Women and patients diagnosed with PC before were excluded. Preoperative PSA levels were 2.05-9.31 ng/mL. Standard RSP and standard pelvic lymphadenectomy were performed.Results: Incidental PC was detected in 22 of 142 patients. The frequency of incidental PC was found to be 15.4% in RSP materials. In 10 of 22 patients with PC, high-grade prostatic intraepithelial neoplasia (PIN) areas were detected. Further, 14 of 120 patients without PC had highgrade PIN zones. In 140 patients, transitional cell carcinoma was detected, and the other 2 patients had signet ring cell carcinoma. In bladder specimens, 68 patients were in the T2 stage, while 58 patients and 16 patients were in the T3 and T4 stages, respectively. The Gleason score (GS) was 2+3=5 in 2 of the 22 incidental PC patients. Moreover, 6 patients had GS of 3+2=5 and 14 patients had GS of 3+3=6. Conclusion:Most incidentally detected PCs in RCP specimens are small, localized, and well-differentiated tumors. Extracapsular extension was not observed in any of them. Patients with invasive bladder tumors and PCs together have a lower T stage than those with only invasive bladder tumors. The risk of PC is higher in patients with invasive bladder cancer than in the healthy population. Preoperative prostate evaluation, prostate dissection, and resection should be performed with oncologic surgery. (JAREM 2016; 6: 15-8)

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Incidental prostate cancer in Asian men: High prevalence of incidental prostatic adenocarcinoma in Chinese patients undergoing radical cystoprostatectomy for treatment of bladder cancer and selection of candidates for prostate‐sparing cystectomy

et al. 2015

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Synchronous primary carcinomas of the bladder and prostate

Cited by 41 publications

References 10 publications

Prevalence of incidental prostate cancer in patients undergoing radical cystoprostatectomy: data from China and other Asian countries

Prevalence of incidental prostate cancer in patients undergoing radical cystoprostatectomy: data from China and other Asian countries

Incidental Prostate Cancer Frequency and Features of Patients Undergoing Radical Cystoprostatectomy

Incidental prostate cancer in Asian men: High prevalence of incidental prostatic adenocarcinoma in Chinese patients undergoing radical cystoprostatectomy for treatment of bladder cancer and selection of candidates for prostate‐sparing cystectomy

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