Synchronous Epidermoid Cyst and Mature Teratoma of the Testis: An Unusual Association

Huyghe, É.; Mazerolles, Catherine; Moran, César A.; Khedis, M.; Khoury, Elias; Nohra, Joe; Soulié, M.; Plante, Pierre

doi:10.1159/000100844

Cited by 5 publications

(4 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most striking finding of the present series is that simple TEC can obviously be mimicked by epidermoid cysts developing in association with full-blown GCT [24]. The association of TEC with ipsilateral GCT has been reported sporadically to date [3, 7, 25, 26]. The association of GCT with contralateral TEC has also been noted [27].…”

Section: Discussionmentioning

confidence: 64%

Testicular epidermoid cysts: a reevaluation

et al. 2019

View full text Add to dashboard Cite

Background Testicular epidermoid cysts (TECs) are rare benign testicular neoplasms. As TECs are rarely associated with germ cell tumours (GCTs), the understanding of biological behaviour and clinical management of TEC is unresolved. Methods We retrospectively searched the files of patients treated for testicular neoplasms and germ cell cancer in the time from 2000 to 2017. Those with TEC were subjected to closer review looking to clinical and histological features, and to results from imaging with ultrasonography (US), contrast enhanced sonography (CEUS) and magnetic resonance imaging (MRI). Results Among 589 patients undergoing surgery for testicular tumour, nine simple TECs were identified (1.5, 95% confidence intervals 0.53–2.50%). Median age was 26 years. Imaging revealed sharply demarcated roundish lesions with avascular central areas. Eight patients underwent testis-sparing excision with no recurrence ensuing. One had orchiectomy because of large size of the mass. Histologically, TECs consisted of cornifying squamous cell epithelium and no accompanying germ cell neoplasia in situ. Two additional cases (0.3% of all) required orchiectomy because these TECs were associated with ipsilateral GCT. Conclusions TEC is usually a benign lesion that can safely be diagnosed with US, CEUS and MRI due to its roundish shape and its avascular centre. Histologically, this TEC corresponds to the prepubertal-type teratoma unrelated to germ cell neoplasia in situ of the 2016 WHO classification. The other subtype of TEC that is associated with invasive GCT represents a teratoma of postpubertal-type. From a clinical point of view it could be easier to differentiate between a “simple TEC” which is benign (prepubertal type) and a “complex TEC” which is malignant because of its association with invasive GCT.

show abstract

Section: Discussionmentioning

confidence: 64%

Testicular epidermoid cysts: a reevaluation

et al. 2019

View full text Add to dashboard Cite

show abstract

“…[8] In a patient with TEC, additional lesions must be sought assiduously because of the possibility of synchronous teratoma. [14] However, the situation is further complicated by the existence of mature teratoma in pre-pubertal boys, which, like TEC, is derived from benign germ cells and, like TEC, is a benign lesion. [15] In this lesion, there is no evidence of intratubular germ cell neoplasia (IGCN), whereas in 90% of the post-pubertal teratomas IGCN is found histologically.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Testicular Epidermoid Cysts

Loberant

Bhatt

Messing

et al. 2011

Journal of Clinical Imaging Science

View full text Add to dashboard Cite

Testicular epidermoid cysts are the most common benign tumors of the testes, but account for only 1-2% of all testicular tumors. In a young man presenting with a testicular mass, a high index of suspicion must be maintained for the malignant testicular germ cell tumor, which is 50-times more common than testicular epidermoid cyst. Bilateral testicular epidermoid cysts are a very rare condition, with only a few reports in the literature. It is extremely important in this condition to make a correct pre-operative diagnosis on imaging to enable a testis-sparing surgery.

show abstract

“…In het kader van testispreservatie voor de fertiliteit en voor het testosteronniveau in de loop van het leven, wordt tegenwoordig aanbevolen te streven naar testissparende therapie indien mogelijk [8,9]. Bij testissparende chirurgie is het advies om, behalve enucleatie van de cyste, ook een vriescoupe in te sturen van het parenchymweefsel en te beoordelen of er geen teratomateuze componenten of (pre)maligne kenmerken aanwezig zijn [10]. Van de tot nu toe gepubliceerde artikelen hebben de patiënten een zeer goede prognose na testissparende chirurgie of radicale orchidectomie [11][12][13][14].…”

Section: Discussieunclassified

Case report. Een benigne zwelling van de testis: een intratesticulaire epidermoïdcyste. Cave: overige echografische afwijkingen

et al. 2018

View full text Add to dashboard Cite

Samenvatting Deze casus betreft een 22-jarige patiënt die zich presenteerde met een niet-pijnlijke, palpabele zwelling van de linker testis. Echografie toonde een typisch beeld met uienringen, met daarnaast een tweetal kleine hypo-echogene laesies als toevalsbevinding. Patiënt onderging daarom een radicale orchidectomie links. Pathologie bevestigde de diagnose 'intratesticulaire epidermoïdcyste', er werd echter ook een seminoom gevonden. Een intratesticulaire epidermoïdcyste is de meest voorkomende afwijking van de testis. Echografie is eerste keus in de diagnostiek, maar hiermee kan de diagnose niet met zekerheid worden gesteld, aangezien een matuur teratoom dezelfde echografische kenmerken kan hebben. Indien er sprake is van alleen een epidermoïdcyste zou kunnen worden volstaan met een afwachtend beleid of een partiële resectie. In het kader van deze casus was een radicale orchidectomie achteraf de juiste keuze, aangezien er ook sprake was van een seminoom. Trefwoorden intratesticulaire epidermoïdcyste • testis • benigne Case report. A benign tumor of the testis: an intratesticular epidermoid cyst. Preserve you from other ultrasound abnormalities Abstract A 22-year-old patient visited our outpatient clinic with a non-painful, palpable swelling of the left testis. Ultrasonography showed suspicion of an intratesticular epidermoid cyst with a hypoechogenic lesion located next to it. The patient underwent a radical orchiectomy. Pathology showed an intratesticular epidermoid cyst and also a small seminoma. An intratesticular epidermoid cyst is the most seen, benign abnormality of the testis. Ultrasound of the testis is the first choice of diagnostics and shows a characteristic onion ring like pattern. Treatment options are follow-up or partial resection. In this specific case, a radical orchiectomy was the good choice because of the seminoma found in the specimen. Keywords intratesticular epidermoid cyst • testis • benign Introductie Een zwelling van het scrotum is een afwijking die dagelijks in de praktijk beoordeeld wordt (bijvoorbeeld een hydrocele drs. Diederick Duijvesz

show abstract

Synchronous Epidermoid Cyst and Mature Teratoma of the Testis: An Unusual Association

Cited by 5 publications

References 10 publications

Testicular epidermoid cysts: a reevaluation

Testicular epidermoid cysts: a reevaluation

Bilateral Testicular Epidermoid Cysts

Case report. Een benigne zwelling van de testis: een intratesticulaire epidermoïdcyste. Cave: overige echografische afwijkingen

Contact Info

Product

Resources

About