Synchronous double malignancies of renal cell carcinoma and acute myeloid leukemia: An unreported co‐existence

Beyan, Cenǵiz; Kaptan, Kürşat; Tunca, Yusuf; İfran, Ahmet; Guran, Sefik

doi:10.1002/ajh.20422

Cited by 1 publication

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, the concurrence of these 3 diseases has not been previously reported. The presence of multiple malignancies is uncommon, and the association is considered to be 'synchronous' if 2 unrelated malignancies occur within 6 months [5] . Renal cell carcinoma is the most commonly reported malignancy in patients with ADPKD [6] .…”

Section: Discussionmentioning

confidence: 99%

Concurrent Renal Cell Carcinoma and Central Nervous System Lymphoma in a Patient with Autosomal Dominant Polycystic Kidney Disease

Chang¹,

Chen²,

Chen³

et al. 2009

Med Princ Pract

View full text Add to dashboard Cite

Objective: To report an unusual case of synchronous renal cell carcinoma and CNS lymphoma in a patient with autosomal dominant polycystic kidney disease (ADPKD). Case Presentation and Intervention: A 58-year-old woman presented with progressive right hemiparesis of 2 months’ duration. A brain CT scan revealed multiple enhanced lesions in the basal ganglia and the right occipital lobe. CNS lymphoma was confirmed by a stereotactic biopsy. Polycystic kidneys and a right renal mass were found incidentally. It was decided to treat the patient with cranial radiotherapy and chemotherapy first. The patient achieved complete remission of CNS lymphoma after 3 months, but the renal mass remained unchanged. A needle biopsy of the renal mass revealed renal cell carcinoma and unilateral nephrectomy was performed successfully. The patient remained in complete remission at 6-year follow-up. Conclusion: The patient was treated successfully with a combination of chemotherapy, radiotherapy, and unilateral nephrectomy. This report highlights the need for clinicians to remain alert to the possibility of double malignancies while caring for ADPKD patients, especially when multiple unexplained manifestations exist.

show abstract

Section: Discussionmentioning

confidence: 99%