Synchronous colorectal liver metastases: a national survey of surgeon opinions on simultaneous resection and multidisciplinary cooperation

Howard, Carrie; Clements, Thomas; Edwards, Janet P.; MacLean, Anthony R.; Buie, W. Donald; Dixon, Elijah; Grondin, Sean C.; Gomes, Anthony; McColl, Michael; Cleary, Sean P.; Jayaraman, Shiva; Daigle, R.; Ball, Chad G.

doi:10.21037/hbsn.2017.12.01

Cited by 12 publications

(7 citation statements)

References 27 publications

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“…Our study represents the largest survey of North American surgeons regarding simultaneous resection and our results on perceived differences in barriers are compatible with clinical practice and a similar, previously published smaller survey. 31 Even though our study may reflect opinion and not actual practice, the internal consistency we found throughout the survey and the logic to responses, conceivably reflect surgeons' perceptions.…”

Section: Discussionmentioning

confidence: 79%

Simultaneous resection of colorectal cancer with synchronous liver metastases; a practice survey

Griffiths

Bogach

Šimunović

et al. 2020

HPB

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Background: We examined surgeon practice intentions and barriers to performing simultaneous resections for colorectal cancer with synchronous liver metastases.Methods: We electronically surveyed North American surgeons who provide colorectal cancer care with a pilot-tested questionnaire. Four clinical scenarios of increasing complexity were presented.Perceived outcomes of and barriers to simultaneous resection were assessed on a 7-point Likert scale.We compared results between general and hepatobiliary surgeons.Results: Responses (rate 20%, 234/1166) included 50 general and 134 hepatobiliary surgeons. High likelihood scores for support of simultaneous resection among general and hepatobiliary surgeons, respectively, included the following for: minor liver and low complexity colon, 83% and 98% (p < 0.001); minor liver and rectal resection, 57% and 73% (p = 0.042); complex liver and low complexity colon resection, 26% and 24% (p = 0.858); and, complex liver and rectal resection, 11% and 7.0% (p = 0.436). Among hepatobiliary surgeons, the most common barriers to simultaneous resections were patient comorbidities and lung metastases, whereas certain general surgeons additionally identified transfer of care.Conclusions: Surgeon support for simultaneous resection was high for cases with minor hepatectomy, and low for cases involving major hepatectomy. These results suggest that clinical trials should involve patients with limited disease to evaluate post-operative complications and cost.

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Section: Discussionmentioning

confidence: 79%

Simultaneous resection of colorectal cancer with synchronous liver metastases; a practice survey

Griffiths

Bogach

Šimunović

et al. 2020

HPB

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“…Furthermore, the survey invitation was indirectly delivered through mass email (CSSO) or mass newsletters (CAGS/CSCRS), in which the eligible members may not have read the invitation to participate in this study, potentially explaining the low numbers of total responses. However, our total number of responses was comparable to another national CRLM survey study that had used CAGS and CSCRS societies for survey delivery to surgeons (response n = 58) [ 28 ]. When interpretating our thematic extraction results, the response bias cannot not be eliminated, as this study may have attracted respondents who have stronger interest in this topic than others.…”

Section: Discussionmentioning

confidence: 66%

Attitudes of Canadian Colorectal Cancer Care Providers towards Liver Transplantation for Colorectal Liver Metastases: A National Survey

et al. 2022

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Up to 50% of colorectal cancer (CRC) patients develop colorectal liver metastases (CRLM). The aim of this study was to gauge the awareness and perception of liver transplantation (LT) for non-resectable CRLM, and to describe the current referral patterns and management strategies for CRLM in Canada. Surgeons who provide care for patients with CRC were invited to an online survey through the Canadian Association of General Surgeons, the Canadian Society of Colon and Rectal Surgeons, and the Canadian Society of Surgical Oncology. Thirty-seven surveys were included. The most utilized management strategy for CRLM was to refer to a hepatobiliary surgeon for assessment of metastectomy (78%), and/or refer to medical oncologists for consideration of chemotherapy (73%). Among the respondents, 84% reported that their level of knowledge about LT for CRLM was low, yet the perception of exploring the option of LT for non-resectable CRLM seemed generally favorable (81%). The decision to refer for consideration of LT for CRLM treatment seemed to depend on patient-specific factors and the local hepatobiliary surgeon’s recommendation. Providing CRC care providers with educational materials on up-to-date CRLM management may help raise the awareness of the use of LT for non-resectable CRLM.

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“…Repeated liver resection of CRCLM can achieve comparable perioperative mortality and long-term survival rates as primary liver resection [39]. For patients with CRC and synchronous liver metastases, simultaneous resection is safe and feasible [40,41]. Prognosis prediction can help identify patients who are most likely to benefit from various treatments.…”

Section: Discussionmentioning

confidence: 99%

Evolutions of the Management of Colorectal Cancer Liver Metastasis: A Bibliometric Analysis

Bao

et al. 2021

J. Cancer

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Background: Tremendous progress has been made in the treatment of colorectal cancer liver metastasis (CRCLM) in recent decades, and thousands of papers have been published. Therefore, we conducted a bibliometric analysis of articles related to CRCLM treatment to explore its evolution. Materials and Methods: The Clarivate Analytics Web of Science (WOS) Core Collection database was searched through June 2020 using terms related to CRCLM treatment. We analyzed the bibliographic information of the literature related to CRCLM treatment and explored the research topics to understand its evolution over time. Results: We identified 3436 records related to CRCLM treatment in the WOS database. The total number of times these documents were cited ranged 0-2352, and the years of publication spanned 1976-2020. The greatest numbers of articles were published in the United States, Japan, and France. Among institutions, Memorial Sloan-Kettering Cancer Center, MD Anderson Cancer Center, and Oslo University Hospital published the most articles. Regarding authors, Jarnagin WR, Adam R, Vauthey JN published the most articles. The research topics of these articles included systemic chemotherapy, molecular targeted therapy, the outcome of liver resection, prognosis prediction, hepatic artery infusion, radiofrequency ablation, and two-stage hepatectomy. Conclusion: Bibliometric analysis of studies related to CRCLM treatment can help doctors and researchers quickly understand the development trend in this field. These data emphasize the current management of patients with CRCLM, and they can potentially guide the direction of future research.

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Synchronous colorectal liver metastases: a national survey of surgeon opinions on simultaneous resection and multidisciplinary cooperation

Abstract: There was general agreement between CRS and general surgeons on numerous topics, but additional education is required with regard to HPB surgical capabilities and to provide truly individualized patient-centered care.

Cited by 12 publications

References 27 publications

Simultaneous resection of colorectal cancer with synchronous liver metastases; a practice survey

Simultaneous resection of colorectal cancer with synchronous liver metastases; a practice survey

Attitudes of Canadian Colorectal Cancer Care Providers towards Liver Transplantation for Colorectal Liver Metastases: A National Survey

Evolutions of the Management of Colorectal Cancer Liver Metastasis: A Bibliometric Analysis

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