Synchronous adenocarcinoma and extranodal natural killer/T-cell lymphoma of the colon: A case report and literature review

Tseng, Chih-En; Shu, Ta-Wen; Lin, Chun-Cheng; Liao, Kai‐Sheng

doi:10.3748/wjg.v19.i11.1850

Cited by 7 publications

(8 citation statements)

References 13 publications

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“…ENKTL-NT occurs primarily in the nasal cavity, and colonic primary cases are even rarer. A MEDLINE search revealed 9 unique cases of colonic primary ENKTL-NT-NT (Table 1) (11)(12)(13)(14)(15)(16)(17)(18)(19) (including the case reported here). In this case report, although the patient was eventually diagnosed with ENKTL-NT, the presenting symptoms were unusual.…”

Section: Discussionmentioning

confidence: 99%

Primary colon natural killer (NK)/T-cell lymphoma, nasal type, with perforations: a case report and literature review

Xie¹,

Liu²,

Wen³

et al. 2021

Ann Palliat Med

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Section: Discussionmentioning

confidence: 99%

Primary colon natural killer (NK)/T-cell lymphoma, nasal type, with perforations: a case report and literature review

Xie¹,

Liu²,

Wen³

et al. 2021

Ann Palliat Med

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“…The etiology is often unclear, and there is no standard treatment strategy. As histopathological subtypes of malignant lymphoma with colorectal cancer synchronously, diffuse large B-cell lymphoma (DLBCL) ( 5 ), mantle cell lymphoma ( 6 ), mucosa-associated lymphoid tissue (MALT) lymphoma ( 7 ), and extranodal natural killer/T-cell lymphoma ( 8 ) have been reported previously. More recently, it has also been reported in FL ( 9 , 10 ).…”

Section: Introductionmentioning

confidence: 99%

Synchronous colon cancer after treatment for rectal follicular lymphoma: A case report

Saito¹,

Egami²,

Kato³

et al. 2022

Mol Clin Oncol

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Colorectal follicular lymphoma (FL) is rare. In addition, it is even rarer that colon cancer develops synchronously with colorectal lymphoma. The present study reports a case of sigmoid colon cancer that developed 6 months after endoscopic resection of rectal FL. A 71-year-old man with a history of developing mucosa-associated lymphoid tissue lymphoma in his stomach at age 48, right neck region at age 59 (the latter later modified as FL) and lung adenocarcinoma at age 60 now suffers from rectal FL. Endoscopic submucosal dissection (ESD) was performed at our hospital (Aiiku Hospital), and 6 months after the treatment, sigmoid colon cancer was confirmed by colonoscopy for the follow-up study. The patient was successfully curatively resected by ESD plus local resection and has survived without a recurrence for >3 years with no treatment. It was speculated that in the present case, cancer-related genes were changed as a carcinogenic mechanism due to decreased immune function associated with the onset of lymphoma.

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“…2 These entities have mostly been reported as case reports, or small case series with very few large studies done. 3-12 They can combine any type of lymphoma or leukemia with a non-hematological neoplasm of any solid organ including skin, all parts of the gastrointestinal tract, brain, lung, kidney, prostate, breast, and so on, and the non-hematological solid organ neoplasm may be a carcinoma or sarcoma. 3-12…”

Section: Introductionmentioning

confidence: 99%

Did I Miss It? Discovering Hidden Coexisting Hematological Neoplasms: A Single Institutional Review of 100 Collision Tumors

et al. 2018

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A collision tumor is defined as two histologically distinct tumor types identified at the same anatomic site. Hematolymphoid proliferative disorders (HLPDs), which coincide with non-hematological neoplasms, can mimic an immune response and can easily be overlooked as an immune reaction to a solid organ neoplasm, especially when low grade. In order to avoid a delay in the diagnosis of a HLPD during the workup for a non-hematological neoplasm, we identified a cohort of 100 cases with a HLPD diagnosis during the initial workup and treatment of a non-hematological neoplasm, or vice versa. Among the 100 collision tumors, the most common non-hematological neoplasms associated with a HLPD were from the colon (17%), breast (15%), and prostate (12%). The most commonly identified HLPDs were chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL; 18%), diffuse large B-cell lymphoma (17%), follicular lymphoma (14%), marginal zone lymphoma (10%), acute myeloid leukemia (8%), and classical Hodgkin lymphoma (5%). Interestingly, in this cohort 5% of the low-grade HLPDs, all of them CLL/SLL, were missed at initial sign-out and subsequently required an addendum report. The other 95% of cases were reviewed or signed out by a hematopathologist before the report was finalized for the non-hematological neoplasm. In summary, high-grade hematological malignancies are less likely to be missed; however, low-grade coexisting HLPDs can be overlooked as a reactive immune response to a solid organ neoplasm. Therefore, it is important to keep in mind the existence of collision low-grade HLPDs before assuming the lymphoid infiltrates as an immunological response.

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Synchronous adenocarcinoma and extranodal natural killer/T-cell lymphoma of the colon: A case report and literature review

Cited by 7 publications

References 13 publications

Primary colon natural killer (NK)/T-cell lymphoma, nasal type, with perforations: a case report and literature review

Primary colon natural killer (NK)/T-cell lymphoma, nasal type, with perforations: a case report and literature review

Synchronous colon cancer after treatment for rectal follicular lymphoma: A case report

Did I Miss It? Discovering Hidden Coexisting Hematological Neoplasms: A Single Institutional Review of 100 Collision Tumors

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