Synchronous Acute Appendicitis and Acute Cholecystitis: A Discussion of a Century's Worth of Epidemiologic, Basic Science, and Clinical Research, Explicating the Pathophysiology of a Likely Underrecognized Historical Condition

Shweiki, Ehyal; Price, Thea P.; Patel, Pankaj H.; Koenig, George; Beekley, Alec C.; Rittenhouse, David; Kaulback, Kellee; Cohen, Murray

doi:10.1177/000313481608201133

Cited by 7 publications

(5 citation statements)

References 4 publications

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“…Physical examination results typically showed tenderness to palpation and Murphy's sign. Many of the physical examinations had a positive McBurney's point in the patient, and CT scans and ultrasound confirmed the combined AA and AC diagnosis, hence suggesting laparoscopic procedures in the patients [11][12][13][14][15][16][17][18][19]. This result is consistent with well-documented common symptoms of AA, which include RLQ pain, and common symptoms of AC, which include pain in the severe RUQ or epigastrium pain and possible radiation to the right shoulder or back [6,7].…”

Section: Discussionmentioning

confidence: 93%

“…However, unlike in the case of combined AA and AC, McBurney's point is only seen in about 50% of patients with isolated AA [3]. The duration of symptoms and abnormalities in vital signs and laboratory results were inconsistent and hence are not a reliable basis of diagnosis in these patients [11][12][13][14][15][16][17][18][19]. Ultrasound is the most often used imaging modality for the initial diagnosis of AC, although CT and MRI are often also performed for possible complications, and laparoscopic cholecystectomy is the gold-standard treatment [1,3,[6][7][8].…”

Section: Sex Age Presenting Complaintsmentioning

confidence: 99%

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Synchronous Acute Appendicitis and Acute Cholecystitis: A Case Report

Kancheva¹,

Neychev²

2023

Cureus

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Acute cholecystitis (AC) and acute appendicitis (AA), independently, are among the most commonly diagnosed conditions in the emergency department (ED). However, their synchronous presentation is very rare. Here, we present a 31-year-old man with worsening right flank abdominal pain, nausea, and vomiting. Physical examination results were significant for moderate to severe right upper abdominal quadrant pain with a positive Murphy's sign and right lower quadrant pain with rebound. Workup in the ED revealed leukocytosis with a left shift, and the abdominal ultrasound and computerized tomography scan showed AA and AC. A literature review revealed a paucity of publications on concomitant AA and AC. Reporting new cases will contribute to improving our understanding of the biology, natural history, and management of this rare pathological combination.

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Section: Discussionmentioning

confidence: 93%

Section: Sex Age Presenting Complaintsmentioning

confidence: 99%

Synchronous Acute Appendicitis and Acute Cholecystitis: A Case Report

Kancheva¹,

Neychev²

2023

Cureus

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“…In our patient, the presentation was more suggestive of ACC rather than acute appendicitis as pain and tenderness were more prominent at the right upper quadrant and the ultrasound image showed multiple small size stones and thickened-wall gallbladder. In the literature, there were some case reports of synchronous presentation of acute appendicitis and cholecystitis [ 14 - 16 ]. Demuro reported a case of synchronous acute cholecystitis and acute appendicitis that was managed laparoscopically [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Appendiceal Adhesion to the Gallbladder Detected During Laparoscopic Cholecystectomy: A Case Report

Busbaih¹,

Busbaih²,

Odeh³

et al. 2021

Cureus

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Acute cholecystitis is a very common acute abdominal disease that mostly indicates abdominal surgery. Appendiceal adhesion to the gallbladder is a very rare condition detected during laparoscopic surgery. A 54-year-old female patient, with a known case of diabetes and hypertension, presented with right upper quadrant abdominal pain of four months’ duration. The pain was increasing in severity and associated with fatty meals. She was diagnosed with acute cholecystitis and was sent to the operating room for laparoscopic cholecystectomy. Appendiceal adhesion to the gallbladder was found, and laparoscopic cholecystectomy and laparoscopic appendectomy were performed. Adhesion of the appendix to the gallbladder should be considered by general surgeons.

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“…Appendicitis is a rare form of presentation of acute abdomen in Salmonella infections (30). The mechanism of Salmonella-induced appendicitis could be pathogen predilection for the appendix or invasion of the appendix from the portal venous system (31). Ultrasound should be used first in patients suspected of having appendicitis, and CT scans should be used judiciously (32).…”

Section: Discussionmentioning

confidence: 99%

Synchronous Acute Acalculous Cholecystitis and Appendicitis Due to Salmonella Group D: A Rare Case Report From China and Review of the Literature

et al. 2020

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Non-typhoidal Salmonella (NTS) disease is not common as typhoid fever but has become a global public health problem in recent decades. Acute acalculous cholecystitis (AAC) and appendicitis are rare complications of NTS infection, which are usually difficult to be diagnosed with atypical signs. Pathogenesis of NTS-induced AAC and NTS-induced appendicitis is still unclear. Ultrasound is the first choice for diagnosis of these two rare complications, computed tomography can assist in and next-generation sequencing (NGS), as a new technology in clinical medicine, also facilitates diagnosis. We described a case of simultaneous AAC and appendicitis due to NTS in an elderly male and further confirmed the diagnosis using NGS. As far as we know, this is the first Asian case of two complications occurring at the same time. Our aim is to alert physicians to pay attention to this rare condition.

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Synchronous Acute Appendicitis and Acute Cholecystitis: A Discussion of a Century's Worth of Epidemiologic, Basic Science, and Clinical Research, Explicating the Pathophysiology of a Likely Underrecognized Historical Condition

Cited by 7 publications

References 4 publications

Synchronous Acute Appendicitis and Acute Cholecystitis: A Case Report

Synchronous Acute Appendicitis and Acute Cholecystitis: A Case Report

Appendiceal Adhesion to the Gallbladder Detected During Laparoscopic Cholecystectomy: A Case Report

Synchronous Acute Acalculous Cholecystitis and Appendicitis Due to Salmonella Group D: A Rare Case Report From China and Review of the Literature

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