Synaptogenesis in the inferior colliculus of the pre-hearing postnatal ferret

Brunso‐Bechtold, Judy K.; Evans, Stephanie D.; Henkel, Craig K.

doi:10.1016/j.heares.2006.03.017

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…Also with age the peaks become sharper and better defined. It is likely that this is caused by increased synchronization in the brain areas processing sound, in parallel with the maturation of the auditory system, as has been demonstrated in pre-hearing postnatal ferrets (Brunso-Bechtold et al, 2006;Harper and Wallace, 1995). The development of the auditory system cannot be isolated from the general development of senses and motor ability in growing kits.…”

Section: Discussionmentioning

confidence: 88%

Development of vocalization and hearing in American mink (Neovison vison).

Brandt

Malmkvist

Nielsen

et al. 2013

Journal of Experimental Biology

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SUMMARYAmerican mink (Neovison vison) kits are born altricial and fully dependent on maternal care, for which the kits' vocalizations appear essential. We used auditory brainstem responses (ABRs) to determine: (1) hearing sensitivity of adult females from two breeding lines known to differ in maternal behaviour and (2) development of hearing in kits 8-52days of age. We also studied sound production in 20 kits throughout postnatal days 1 to 44. Adult female mink had a broad hearing range from 1kHz to above 70kHz, with peak sensitivity (threshold of 20dB SPL) at 8-10kHz, and no difference in sensitivity between the two breeding lines (P>0.22) to explain the difference in maternal care. Mink kits showed no signs of hearing up to postnatal day 24. From day 30, all kits had ABRs indicative of hearing. Hearing sensitivity increased with age, but was still below the adult level at postnatal day 52. When separated from their mothers, kits vocalized loudly. Until the age of 22days, 90% of all kits vocalized with no significant decline with age (P=0.27). From day 25, concurrent with the start of hearing, the number of vocalizing kits decreased with age (P<0.001), in particular in kits that were re-tested (P=0.004). Large numbers of mink are kept in fur industry farms, and our results are important to the understanding of sound communication, which is part of their natural behaviour. Our results also suggest mink as an interesting model for studying the development of mammalian hearing and its correlation to sound production.

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Section: Discussionmentioning

confidence: 88%

Development of vocalization and hearing in American mink (Neovison vison).

Brandt

Malmkvist

Nielsen

et al. 2013

Journal of Experimental Biology

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Developmental changes of the protein repertoire in the rat auditory brainstem: A comparative proteomics approach in the superior olivary complex and the inferior colliculus with DIGE and iTRAQ

Kaltwaßer

Schulenborg

Beck

et al. 2013

Journal of Proteomics

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Development of banded afferent compartments in the inferior colliculus before onset of hearing in ferrets

et al. 2007

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Axonal projections from the lateral superior olivary nuclei (LSO), as well as from the dorsal cochlear nucleus (DCN) and dorsal nucleus of the lateral lemniscus (DNLL), converge in frequency-ordered layers in the central nucleus of the inferior colliculus (IC) where they distribute among different synaptic compartments. A carbocyanine dye, DiI, was used as a tracer to study the postnatal development of axonal projections in the ferret IC. The results indicated that projections from all three nuclei are present at birth, but are not segregated into bands. During the postnatal week between approximately postnatal days 4 and 12 (P4-P12), axons from LSO proliferate in IC, become more branched, and segregate into a series of bands composed of densely packed fibers and endings. LSO projections in these afferent bands course parallel to IC layers and are separated by intervening regions with few endings. A modest fit of a sine curve (R 2 >0.15) to the pattern of spacing of LSO projections in IC indicated that regularly spaced bands are forming by P7. Similarly, banded patterns of DCN and DNLL projections to IC have developed by the end of the first postnatal week. Thus, well before hearing onset in ferret (P28-30), three different afferent projections have segregated into banded compartments along layers in the central nucleus of the ferret IC. Possible mechanisms in circuit development are discussed.

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Synaptogenesis in the inferior colliculus of the pre-hearing postnatal ferret

Cited by 3 publications

References 10 publications

Development of vocalization and hearing in American mink (Neovison vison).

Development of vocalization and hearing in American mink (Neovison vison).

Developmental changes of the protein repertoire in the rat auditory brainstem: A comparative proteomics approach in the superior olivary complex and the inferior colliculus with DIGE and iTRAQ

Development of banded afferent compartments in the inferior colliculus before onset of hearing in ferrets

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