Symptoms, physical findings and bronchial hypersensitivity in patients with bronchial asthma and normal spirometry

Abstract

There is a correlation with lung pathologic physical findings, lower values of FEV1 (in a range of normal values) and the degree of nonspecific bronchial sensitivity as objective indices of activity of bronchial asthma. There is no correlation of these parameters with patient's symptoms as subjective indices of bronchial asthma.

Guidance on the diagnosis and management of asthma among adults in resource limited settings

“…HCWs should remember that symptoms and signs described above can occur in disease states other than asthma [12][13][14] . Other diseases with asthma-like symptoms to consider before establishing diagnosis of asthma include: chronic obstructive pulmonary disease (COPD), hyperventilation syndrome, congestive heart failure,pulmonary embolism, mechanical obstruction of the airways (such as occurs in tumours of the lung), vocal cord dysfunction and cough secondary to drugs (e.g.…”

Bronchial asthma - from psychosomatic illness to proinflammatory cytokines and asthma phenotypes

“…For clinical practice, asthma will continue to be a challenge in patients with a history of chronic symptoms and who have a normal pulmonary ventilation determined by the spirometric test and negative tests to bronchial hyperreactivity because some of them already have intermittent asthma (which due to the spontaneous variability of symptoms, inflammation and hypersensitivity remains undiagnosed and untreated) 31,32 .…”