Symptoms and signs in fibromyalgia syndrome

Abstract

RIASSUNTOLa sindrome fibromialgica (FM)

Depression symptoms are associated with key health outcomes in women with fibromyalgia: a cross-sectional study

“…People with fibromyalgia (FM) are characterized by diffuse and widespread musculoskeletal pain which may influence their daily activities. FM significantly reduces health‐related quality of life (HRQoL) compared to healthy people and people with other rheumatic diseases .…”

Fibromyalgia and arthritides

“…The most frequent and typical symptoms of FM are generalised pain, stiffness, fatigue, and poor sleep (9), but the defining symptom is widespread chronic pain lasting at least three months, usually in all four limbs and the upper or lower back. The pain has been described in many ways (burning, searing, tingling, shooting, stabbing, deeply aching, sharp, or "feeling bruised all REVIEW Fibromyalgia and arthritides over") and, like stiffness, it is often worsened by cold or damp weather, anxiety or stress, excessive or too little physical activity, poor sleep, and noise (1,9). About 65% of the patients say they "hurt all over", and this may be useful in differentiating FM from other conditions (8,9).…”

“…The pain has been described in many ways (burning, searing, tingling, shooting, stabbing, deeply aching, sharp, or "feeling bruised all REVIEW Fibromyalgia and arthritides over") and, like stiffness, it is often worsened by cold or damp weather, anxiety or stress, excessive or too little physical activity, poor sleep, and noise (1,9). About 65% of the patients say they "hurt all over", and this may be useful in differentiating FM from other conditions (8,9). However, musculoskeletal pain is common in patients with rheumatic diseases, and it is not always easy to discover its cause.…”

“…However, musculoskeletal pain is common in patients with rheumatic diseases, and it is not always easy to discover its cause. Pain is certainly the cornerstone of a diagnosis of FM, but it is accompanied an array of multi-system symptoms that are common to various musculoskeletal conditions (such as fatigue, Raynaud's phenomenon, sleep disturbances, muscle stiffness, sicca syndrome, irritable bowel disease, depression and anxiety), and the absence of specific laboratory findings can easily lead to a misdiagnosis (9,10). As FM-like symptoms are frequently encountered, differential diagnoses against other causes of chronic pain are essential (8).…”

“…Patients with RA should undergo a careful clinical examination in order to evaluate the clinical association with FM, optimise therapy, reduce healthcare costs. Pain, fatigue and stiffness are common in RA, and FM plays a major role (9,16). Wolfe and Michaud (21) found that 17% of their RA patients had FM, and that their RA was more subjectively and objectively severe.…”