Symptoms and signs in culture‐proven acute maxillary sinusitis in a general practice population

Wang

et al. 2016

Sci Rep

Few studies have investigated the relationship between chronic rhinosinusitis (CRS) and erectile dysfunction (ED). This case-control study aimed to investigate the association between CRS and the risk of ED in a large national sample. Tapping Taiwan’s National Health Insurance Research Database, we identified people 30 years or older with a new primary diagnosis of CRS between 1996 and 2007. The cases were compared with sex- and age-matched controls. We identified 14 039 cases and recruited 140 387 matched controls. Both groups were followed up in the same database until the end of 2007 for instances of ED. Of those with CRS, 294 (2.1%) developed ED during a mean (SD) follow-up of 3.20 (2.33) years, while 1 661 (1.2%) of the matched controls developed ED, mean follow up 2.97 (2.39) years. Cox regression analyses were performed adjusting for sex, age, insurance premium, residence, hypertension, hyperlipidemia, diabetes, obesity, coronary heart disease, chronic kidney disease, chronic obstructive pulmonary disease, asthma, allergic rhinitis, arrhythmia, ischemic stroke, intracerebral hemorrhage, and medications. CRS was revealed to be an independent predictor of ED in the fully adjusted model (HR = 1.51; 95% CI = 1.33–1.73; P < 0.0001).

Section: Discussionmentioning

confidence: 85%

Chronic Rhinosinusitis Associated with Erectile Dysfunction: A Population-Based Study

Wang

et al. 2016

Sci Rep

“…26 Elevated C-reactive protein values have been documented in acute maxillary sinusitis. 27 There is increased activation of thrombin coagulation system in the nasal mucosa of chronic rhinosinusitis patients while fibrinolytic inhibiting protein is 28,29 All of the evidence supports the theory that sinusitis is an inflammatory entity that is strongly associated with stroke.…”

Section: Discussionmentioning

confidence: 78%

Dietary polyphenols affect MUC5AC expression and ciliary movement in respiratory cells and nasal mucosa

Chao

Hao

et al. 2012

am j rhinol allergy

“…The inclusion of patients took place from 27 April 1992 to 28 February 1994. Data from the study have been published elsewhere previously (1, 14). Patients aged 18–65 years suspected of having AMS by their general practitioner (GP) were consecutively included once during the study period.…”

Section: Methodsmentioning

confidence: 99%

The association between paranasal computerized tomography scans and symptoms and signs in a general practice population with acute maxillary sinusitis

Hansen¹,

Lund²

2010

Apmis

Self Cite

The objective of this study was to evaluate the association between changes revealed by computerized tomography scan (CT) and symptoms, signs, and bacteriological diagnoses in a general practice population who had been diagnosed with acute maxillary sinusitis (AMS). This study was designed as a prospective cohort study in Danish general practice in cooperation with the otorhinolaryngology and neuroradiology departments at Aalborg County Hospital. One hundred and seventy-four patients, aged 18-65 years, suspected of having AMS were included. The strongest associations were with purulent nasal discharge, preceding upper respiratory tract infection, maxillary toothache and oedema over the maxillary sinuses. Self-reported previous sinusitis was negatively associated with sinus infection. There was a strong association between increasing values of C-reactive protein (CRP) and erythrocyte sedimentation rate and changes on the CT scan. CT scans contributed only little to the final diagnosis, whereas increased CRP values and elevated erythrocyte sedimentation rates were more reliable indicators of inflammation in the sinuses.