Symptomatology and allergen types in patients presenting with allergic rhinitis

Nepali, Rajendra; Sigdel, Brihaspati; Baniya, Prabha

doi:10.3329/bjo.v18i1.10411

Cited by 3 publications

(4 citation statements)

References 14 publications

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“…This is similar to findings by Ajiya, et al, Azam et al 4,19 irrespective of the varying prevalence across the worldwide populations and societies it have shown that the strongest risk factor for the development of allergic symptoms has been a strong family history of allergic disease. 4 The most common triggering factor of allergic rhinitis is dust particle (50.55%) which is concomitant with other observation done by Ajiya et al, Nepali, et al 4,20 The majority of patients in this study presented with complaints of running nose 96.66% which is consistent with other study done by Azam et al 19 However, the symptom with most severity was nasal itching (n= 155) followed by nasal obstruction (n=144) & sneezing (n= 122). These findings differs from other reported findings in Nijeria, India, Brazil, Nepal.…”

Section: Discussionsupporting

confidence: 57%

“…These findings differs from other reported findings in Nijeria, India, Brazil, Nepal. 4,12,16,20 Studies on antihistamines are usually conducted in countries where the presence of seasonal rhinitis is quite significant. The TNSS is a widely accepted and reliable parameter to assess the efficacy of a drug in the treatment of allergic rhinitis.…”

Section: Discussionmentioning

confidence: 99%

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Non-sedative Antihistamines: Assessment of Efficacy Based on Total Nasal Symptom Score in Patient with Allergic Rhinitis.

Islam

Jannat²,

Islam³

et al. 2022

KYAMC j.

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Background: Allergic rhinitis is a common and chronic immunoglobulin E–mediated respiratory disorder following allergen exposure that can affect the quality of life and work activities. Antihistamine should be prescribed for the relief of persistent allergic symptoms & advised to avoid known allergens also. Objectives: The objective of the study is to assess the efficacy of non-sedating antihistamines in the treatment of allergic rhinitis based on the total nasal symptom score. Materials and Methods: This is a prospective study of patients with clinically diagnosed allergic rhinitis following inclusion & exclusion criteria at the study center. Patients’ demographic profiles, symptoms and signs were obtained using a specially designed form. The symptoms were scored from baseline to end of treatment by using nasal symptom scoring protocol. The data were collated and analyzed using Microsoft excel & SPSS Version 17 statistical software. Results: Recruited 360 patients with allergic rhinitis, 96.66% presented with running nose as the chief complaint. A large number of patients have total nasal symptom scores of above 9 (n =170; 47.22%), whereas few (n = 42; 11.66%) had symptom scores of below 6 at a baseline level. Upon treatment with rupatadine, a significant reduction of TNSS (p< 0.05) was found from baseline over the 14-day treatment period. The incidence of adverse effects (fatigue 1.3%, headache 2.7%) was found to be less in the rupatadine group. Conclusion: non-sedative antihistamines effectively control persistent allergic rhinitis, where rupatadine is a drug of choice due to its better efficacy and having a low incidence of side effects. KYAMC Journal. 2022;12(04): 231-236

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Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Non-sedative Antihistamines: Assessment of Efficacy Based on Total Nasal Symptom Score in Patient with Allergic Rhinitis.

Islam

Jannat²,

Islam³

et al. 2022

KYAMC j.

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“…For example, one study gives idea of etiology and some major allergen but not about subgroup of allergen. 9 Another article identified subgroup of allergens, but range of allergens selected was very small and many locally available allergens were not included. 10 We hypothesise that pattern of distribution of allergic diseases vary across the country due to variation in climate and locally available allergens.…”

Section: Original Research Articlementioning

confidence: 99%

Common allergens in patients of allergic rhinitis in Gandaki province of Nepal

Nepali

Sigdel

Dubey³

et al. 2022

JGMC Nepal

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Introduction: Atopic disorder is very common globally and in Nepal which has affected quality of life resulting into loss of working and school days. Change in lifestyle is one of the important recommendations for fighting back with allergy, which suggests for avoidance of allergens developing allergic rhinitis. The objectives of the study were to find out common allergic conditions in Pokhara, Nepal and to identify the allergens, which induced IgE mediated disorder. Methods: A retrospective study was done among the patients with different allergic disorders who were referred from different specialist clinic attending Pokhara ENT Center at Pokhara from January 2011 to December 2017. The study sample included 1810 patients to find the distribution of various allergic disorders among them. Further, a sample of 430 patients of allergic rhinitis who had undergone skin prick test according to international guidelines were included in order to find out the common allergens among them. Set of allergens included in this study were mites, pollen, fungus, insects, dusts, epithelia-danders, feather & fabric, non-juicy foods, and juicy foods. These nine allergen types further included several allergens. Data were analyzed using descriptive statistics using Stata 15.1. The study was done from after taking ethical clearance from the institutional ethical committee of Gandaki medical college. Results: Among various types of allergic diseases, allergic rhinitis accounted for one fourth (23.8%) of the cases. The patients with allergic rhinitis who underwent skin prick test against various allergens were evaluated. Skin prick test positive test result were seen for non-juicy foods (96%), pollens (95%) and then juicy foods (93%). On the contrary, least percentage (13.72%) of people were found positive against feather & fabrics. Radish (7.7%) and snake gourd (6.99%) were only two juicy vegetables against which people were found positive in skin prick test. Among non-juicy foods, tobacco was the commonest allergens which was reported positive in skin prick test of 16% people. Pollen of Zea mays, Azadirachta indica, Mangifera indica and Prosopis juliflora were top allergens diagnosed positive among 12.65%, 10.95%, 7.79%, and 7.54% of people respectively. The mite Dermatophagoides pteronyssinus yielded highest prevalence (69.36%) of positive test. Conclusions: Based upon the findings of our study, allergic rhinitis is one of the most common allergic diseases in Gandaki province, Nepal. Patients of allergic rhinitis should be tested for certain allergens which are locally present and they need to modify lifestyle and avoid allergens which can induce IgE-mediated disorder. Further research is needed to establish causation.

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“…OR arising from workers inhaling colophony employed in the electronic industry is more common among female workers (24%) than males (9%). [25] Healthcare workers are at risk of OR due to possible exposure to different allergens, including formaldehyde, glutaraldehyde, drugs, natural rubber latex (gloves), while working in a hospital environment. A dentist developed OR from inhaling Nobetec, which is a temporary dental filling material that contains colophony.…”

Section: Risk Factors and Causes Of Occupational Rhinitismentioning

confidence: 99%

Occupational rhinitis revisited: Emphasis on the risk factors in Saudi industry

Ballal

2016

Saudi J Med Med Sci

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The European Academy of Allergy and Clinical Immunology (EAACI) Task Force defines occupational rhinitis (OR) as “an inflammatory disease of the nose, which is characterized by intermittent or persistent symptoms (i.e., nasal congestion, sneezing, rhinorrea, itching), and/or variable nasal airflow limitation and/or hypersecretion arising out of causes and conditions attributable to a particular work environment and not to stimuli encountered outside the workplace.” The objectives of this review are to highlight the causes of OR in industrial settings in Saudi Arabia in order to alert primary healthcare physicians and other healthcare providers of the importance of diagnosing and managing OR to prevent further complications and present to the General Organization for Social Insurance (GOSI) evidence of the existence of OR in Saudi industrial sector. The literature search yielded no publications from Saudi Arabia that have investigated the prevalence of OR, but it is expected to be high judging from the high prevalence of allergic rhinitis in the country. The occupational groups that are at risk of developing OR include workers in the petrochemical industry, healthcare personnel, livestock and bird breeders, bakers, farmers, housewives and other occupations all of which are present in Saudi Arabia. Clinic and industry based research within Saudi Arabia is recommended to determine the prevalence of OR and to alert healthcare providers to suspect OR in all symptomatic working adults, including housewives and domestic helpers. Use of EAACI algorithm for the diagnosis and management of this condition will help to manage the condition and prevent the deterioration and further complications. Furthermore, diagnosis using internationally recognized guidelines and the results of the suggested epidemiologic surveys may convince GOSI to recognize OR as an occupational disease.

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Symptomatology and allergen types in patients presenting with allergic rhinitis

Abstract: Abstract

Cited by 3 publications

References 14 publications

Non-sedative Antihistamines: Assessment of Efficacy Based on Total Nasal Symptom Score in Patient with Allergic Rhinitis.

Non-sedative Antihistamines: Assessment of Efficacy Based on Total Nasal Symptom Score in Patient with Allergic Rhinitis.

Common allergens in patients of allergic rhinitis in Gandaki province of Nepal

Occupational rhinitis revisited: Emphasis on the risk factors in Saudi industry

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