Symptomatic reinfection with COVID-19

Vora, Tanisha; Vora, Pragnesh; Vora, Falguni; Sharma, Kamal; Desai, Hardik D

doi:10.4103/jfmpc.jfmpc_2002_20

Cited by 8 publications

(5 citation statements)

References 13 publications

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“…Since the emergence of the novel coronavirus, SARS-CoV-2, our understanding of its dynamics and the immune response it elicits has evolved. While initial assumptions suggested that infection with COVID-19 would confer long-lasting immunity, increasing evidence has demonstrated the possibility of reinfection [14,15]. This one of the first reports of reinfection with SARS-CoV-2 in Saudi Arabia, although few reports have shown some cases in other countries.…”

Section: Discussionmentioning

confidence: 85%

Incidence of Recurrent SARS-CoV-2 Infections during the COVID19 Pandemic in Madina, Saudi Arabia

Elbadawy,

Khattab,

Aljohani

et al. 2023

J. Pharm. Res. Int.

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Background: SARS-CoV-2 infections emerged in China and spread globally causing the Corona virus disease 2019 (COVID19) pandemic. Dispersed reports from different countries reported the possibility of the incidence of SARS-CoV-2 reinfection in individual reported cases. The aim of this report was, therefore, to document several recurrent infection cases in Saudi Arabia to furtherly augment this body of evidence. Methods: The study was conducted retrospectively from October 2020 to October 2021. The study included patients who had experienced multiple COVID-19 infections, which were confirmed through qPCR tests. There was a minimum gap of three months between each infection, and the patients had tested negative after each infection. Personal or phone interviews were conducted with the patients. Results: In total, 10 cases (7 males and 3 females) of COVID19 recurrent infections were reported with an average age of 34.1 years. The most common symptoms included fever, headache, body aches, sore throat, cough, diarrhea. With the exception of one case that required hospitalization during the third infection and one case of miscarriage during the first infection, all reported cases were mild. The average duration of illness for the first infection was 13.9 days, while for the second infection, it was 12.9 days. Only one patient reported being vaccinated before his second course of infection. Conclusion: Infection with COVID-19 does not provide life-long protection. The possibility of recurrent and repeated reinfection with COVID-19 was presented in several cases especially in healthcare workers, indicating that screening of COVID19 infection in hospitals and healthcare centers is essential.

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Section: Discussionmentioning

confidence: 85%

Incidence of Recurrent SARS-CoV-2 Infections during the COVID19 Pandemic in Madina, Saudi Arabia

Elbadawy,

Khattab,

Aljohani

et al. 2023

J. Pharm. Res. Int.

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“…Reinfections cases in the literature show us reinfections might be milder or severe compared to the first infection. However, the reasons for these different situations are not known well (10)(11)(12)(13)(14). Amino acid mutation D614G in the S protein along with P314L in the RdRp of the ORF was present in all the sequences.…”

Section: Discussionmentioning

confidence: 98%

“…The first case of reinfection was reported in Hong Kong in August 2020, and since then, several similar cases were published. As of January 2021, cases of COVID-19 reinfection were reported in Hong Kong, The Netherlands, Belgium, Ecuador, Israel, India, Australia and the United States (10)(11)(12)(13)(14).…”

Section: Discussionmentioning

confidence: 99%

Two cases of COVID-19 reinfection in Turkey

Kalkan¹,

Mohammed²,

Çınar³

et al. 2021

Infect Dis Clin Microbiol

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It is not clear whether re-infection by SARS-CoV-2 occurs as a rare event or not, but since the start of the pandemic limited number of re-infection has been reported. This study reports the clinical presentations and comperative genome analysis of two patients who were suspected of re-infection. The patients showed mild clinical symptoms and varied antibody test results in the two episodes of infections. New generation sequencing of the isolates revealed the presence of different mutations between isolates from the previous and last infections. Therefore it is important to monitor these mutations and assess their capacity of evading previously occurred antibodies.

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“…Unlike most of the other cases reported, our patient developed symptoms of HZ at a relatively younger age and few weeks after recovery from the symptomatic reinfection of COVID-19. Literature is now buzzing with symptomatic reinfection of COVID-19 [ 16 ]. His recovery was confirmed with a negative RT-PCR test for symptomatic reinfection of SARS-CoV-2, lack of immunoglobulin (IgM), and presence of IgG antibodies against SARS-CoV-2.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Herpes Zoster in an Adult Patient Recovered From Symptomatic Reinfection of COVID-19

Ghosh¹,

Gajjar²,

Modi³

et al. 2021

Cureus

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In coronavirus disease 2019 (COVID-19) patients, various dermatological conditions have been observed. Varicella zoster virus (VZV) and herpes simplex virus must be ruled out before considering vesicular exanthems linked to COVID-19. The immunological status of the host has an impact on the natural history of herpes zoster (HZ). Age is a major risk factor for most of the cases of HZ. Reactivation of VZV can be triggered by iatrogenic immunosuppression or disease-related immunocompromised state or age-related immunosenescence. Rarely, dermatological symptoms have been reported in recovered COVID-19 patients. We hereby present a rare case of HZ in a recovered patient from symptomatic reinfection of COVID-19.

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Symptomatic reinfection with COVID-19

Cited by 8 publications

References 13 publications

Incidence of Recurrent SARS-CoV-2 Infections during the COVID19 Pandemic in Madina, Saudi Arabia

Incidence of Recurrent SARS-CoV-2 Infections during the COVID19 Pandemic in Madina, Saudi Arabia

Two cases of COVID-19 reinfection in Turkey

A Rare Case of Herpes Zoster in an Adult Patient Recovered From Symptomatic Reinfection of COVID-19

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