Symptomatic Perianeurysmal Edema Following Bare Platinum Embolization of a Small Unruptured Cerebral Aneurysm

Abstract

SUMMARY:There is considerable interest in the development of symptomatic inflammatory reactions following coil embolization of cerebral aneurysms. Patients have experienced a range of adverse events, usually after treatment of moderately large aneurysms with modified "bioactive" coils. More recently, it has been recognized that adverse inflammatory reactions can be associated with the use of "nonbioactive" coils, and we present a case of symptomatic perianeurysmal edema after treatment of a small unruptured aneurysm with bare platinum coils.

Prospective Study of Early MRI Appearances following Flow-Diverting Stent Placement for Intracranial Aneurysms

“…9,10 Our study showed that while perianeurysmal edema can occasionally occur following flow diversion, it is usually mild.…”

Cytokine and Growth Factor Concentration in Cerebrospinal Fluid from Patients with Hydrocephalus Following Endovascular Embolization of Unruptured Aneurysms in Comparison with Other Types of Hydrocephalus

“…Possibly inflammatory-mediated complications, such as edema visible under magnetic resonance imaging [3][4][5][6][7], aseptic meningitis [8][9][10], and communicating hydrocephalus [5,11,12], have been observed after embolization of unruptured aneurysms. While hydrocephalus after subarachnoid hemorrhage (SAH) is a common and well described, if not well understood, phenomenon [13]; the occurrence of hydrocephalus following treatment of unruptured aneurysms is unexpected.…”

Perianeurysmal vasogenic oedema (PAVO) following aneurysm embolisation: a unique case of asymptomatic long-term progression and review of the literature

“…These early-onset cases seemingly have no relationship to resolution; one case with PAVO onset at day 4 resolved at day 9,15 one case with PAVO onset day 1 remained present and stable at 12 months,4 and the remainder of these early onset cases resolved within 1–5 months. The majority of the remainder of the published cases have PAVO onset within 1–4 weeks12 or beyond 1 month4 7 8 16 and either resolve or near completely resolve by 5–12 months 7 8 12 16. Of eight cases not associated with aneurysm recanalisation, maximal PAVO was observed at a median of 6 months (range 1–6), and complete resolution was seen in four cases at 5, 6, 11 and 61 months, with a further one being partially resolved at 12 months and the remaining three remaining stable with follow-up of 6, 12 and 36 months, respectively.…”

“…PAVO-related seizures were successfully treated with anticonvulsants alone,12 corticosteroids alone8 or as a combination 16…”