Symptomatic overlap between irritable bowel syndrome and microscopic colitis

Limsui, David; Pardi, Darrell S.; Camilleri, Michael; Loftus, Edward V.; Kammer, Patricia P.; Tremaine, William J.; Sandborn, William J.

doi:10.1002/ibd.20059

Cited by 150 publications

(87 citation statements)

References 52 publications

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“…There were four studies reporting the prevalence of IBS symptoms in patients with MC, 41,44,48,49 two of which were case series, 44,48 one a case-control study, 49 and one a cross sectional survey. 41 There were three cross-sectional surveys reporting the prevalence of MC in patients with IBS, 14,41,42 one of which also reported the prevalence of IBS in patients with MC and was included in the aforementioned analysis.…”

Section: Resultsmentioning

confidence: 99%

“…41,44,48,49 Detailed characteristics of these studies are provided in Table 1. To define IBS, three studies used the Rome II criteria, 44,48,49 and one used the Rome III criteria.…”

Section: Prevalence Of Ibs Symptoms In Patients With MCmentioning

confidence: 99%

“…41,44,48,49 Detailed characteristics of these studies are provided in Table 1. To define IBS, three studies used the Rome II criteria, 44,48,49 and one used the Rome III criteria. 41 There were a total of 420 individuals with histologically confirmed MC recruited into these studies, and the pooled prevalence of IBS in all four studies was 33.4% (95% CI 17.2% to 52.0%), but with significant heterogeneity between studies (I 2 =93.6%, P < 0.001).…”

Section: Prevalence Of Ibs Symptoms In Patients With MCmentioning

confidence: 99%

“…41 We contacted authors of another two studies in order to try to obtain these data, but unfortunately these were not available. 48,49 Two of the four studies also reported the prevalence of IBS among other patients with diarrhea in whom random colonic biopsies were normal. 41,49 These studies included a total of 218 patients with MC, of whom 85 (39.0%) had IBS, compared with 129 (20.3%) of 636 patients without MC.…”

Section: Prevalence Of Ibs Symptoms In Patients With MCmentioning

confidence: 99%

See 3 more Smart Citations

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta-analysis

Kamp

Kane

Ford

2016

Clinical Gastroenterology and Hepatology

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Section: Resultsmentioning

confidence: 99%

“…41,44,48,49 Detailed characteristics of these studies are provided in Table 1. To define IBS, three studies used the Rome II criteria, 44,48,49 and one used the Rome III criteria.…”

Section: Prevalence Of Ibs Symptoms In Patients With MCmentioning

confidence: 99%

Section: Prevalence Of Ibs Symptoms In Patients With MCmentioning

confidence: 99%

Section: Prevalence Of Ibs Symptoms In Patients With MCmentioning

confidence: 99%

See 2 more Smart Citations

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta-analysis

Kamp

Kane

Ford

2016

Clinical Gastroenterology and Hepatology

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“…It is described that MC impairs health-related quality of life (HRQOL) [6]. Several studies have shown a symptomatic overlap between MC and irritable bowel syndrome (IBS) [7,8], and the combination of these two diseases further impairs gastrointestinal symptoms and psychological well-being [8]. The great overlap between IBS and MC, the fact that 63% of MC patients only have a single attack of diarrhoea, and the wide range of conditions rendering secondary MC, may lead to an inaccurate diagnose-setting [1,3,9].…”

Section: Introductionmentioning

confidence: 99%

Diarrhoea is not the only symptom that needs to be treated in patients with microscopic colitis

Roth¹,

Bengtsson²,

Ohlsson³

2013

European Journal of Internal Medicine

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Diarrhoea is not the only symptom that needs to be treated in patients with microscopic colitis. Link to publication Citation for published version (APA): Roth, B., Bengtsson, M., & Ohlsson, B. (2013). Diarrhoea is not the only symptom that needs to be treated in patients with microscopic colitis. European Journal of Internal Medicine, 24(6), 573-578. DOI: 10.1016573-578. DOI: 10. /j.ejim.2013 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal

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Irritable Bowel Syndrome

Ford

Martin

Talley

2010

Evidence‐Based Gastroenterology and Hepatology

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INTRODUCTION: The prevalence of irritable bowel syndrome (IBS) varies depending on the criteria used to diagnose it, but it ranges from about 5% to 20%. IBS is associated with abnormal gastrointestinal motor function and enhanced visceral perception, as well as psychosocial and genetic factors. People with IBS often have other bodily and psychiatric symptoms, and have an increased likelihood of having unnecessary surgery compared with people without IBS. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments in people with IBS? We searched: Medline, Embase, The Cochrane Library, and other important databases up to August 2011 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 27 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: 5HT 3 receptor antagonists (alosetron and ramosetron), 5HT 4 receptor agonists (tegaserod), antidepressants (tricyclic antidepressants and selective serotonin reuptake inhibitors [SSRIs]), antispasmodics (including peppermint oil), cognitive behavioural therapy (CBT), hypnotherapy, loperamide, and soluble and insoluble fibre supplementation. QUESTIONS To be covered in future updates Probiotics Key points• The key features of irritable bowel syndrome (IBS) are chronic, recurrent abdominal pain or discomfort, associated with disturbed bowel habit, in the absence of any structural abnormality to account for these symptoms.The prevalence of IBS varies depending on the criteria used to diagnose it, but it ranges from about 5% to 20%.IBS is associated with abnormal GI motor function, enhanced visceral perception, abnormalities in central pain processing, and altered gut flora, as well as psychosocial and genetic factors.People with IBS often have other bodily and psychiatric symptoms, and have an increased likelihood of having unnecessary surgery compared with people without IBS.A positive symptom-based diagnosis and a graded general treatment approach are cornerstones in the management of people with IBS.• Antidepressants (tricyclic antidepressants and SSRIs) may reduce global symptoms of IBS and abdominal pain compared with placebo.• Antispasmodics (including peppermint oil) may reduce global symptoms of IBS and abdominal pain compared with placebo.• We don't know whether soluble fibre supplementation (ispaghula) is more effective than placebo at improving global symptoms or abdominal pain in IBS as the data are contradictory.• Insoluble fibre supplementation does not reduce global symptoms o...

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Symptomatic overlap between irritable bowel syndrome and microscopic colitis

Cited by 150 publications

References 52 publications

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta-analysis

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta-analysis

Diarrhoea is not the only symptom that needs to be treated in patients with microscopic colitis

Irritable Bowel Syndrome

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