Symptomatic Choroidal Neovascularization in Blacks

Capone, Antonio; Wallace, R. Trent; Meredith, Travis A.

doi:10.1001/archopht.1994.01090200097029

Cited by 24 publications

(6 citation statements)

References 22 publications

(4 reference statements)

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“…Clinical manifestations only occur if the membrane extends over the macula, if the vessels haemorrhage into the subretinal space, or fluid exudation occurs within the macula. 3 PCNM can be described either by extent (comparing its size in relation to the optic disc) or circumferentially (how many clock hours of the optic disc circumference is involved). Larger PCNMs have the added complication of causing visual loss by inducing scar contraction, haemorrhage, and further aggressive fibrovascular growth.…”

Section: Introductionmentioning

confidence: 99%

Treating peripapillary choroidal neovascular membranes: a review of the evidence

Jutley

Tah

Lindfield

et al. 2011

Eye

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Peripapillary choroidal neovascular membranes (PCNM) are defined as a collection of new choroidal blood vessels, any portion of which lies within one disc diameter of the nerve head. There are two types of PCNM, and correct pre-interventional identification of growth site has been shown to stratify the chance of visual improvement following therapy. Clinical manifestations occur only where the membrane extends over the macula, if the vessels haemorrhage into the subretinal space or fluid exudation occurs within the macula. This review provides an update and overview on the diverse range of current treatment studies and strategies being used in present clinical ophthalmic practice.

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Section: Introductionmentioning

confidence: 99%

Treating peripapillary choroidal neovascular membranes: a review of the evidence

Jutley

Tah

Lindfield

et al. 2011

Eye

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“…Disciform-stage CNV in blacks was associated with a greater degree of pigment proliferation than that typically noted in whites. Demographically, there was a significant female predominance of CNV in blacks (87%) compared with population studies [54]. In Vancouver a total of 88 ethnic Chinese patients were identified among 10,000 angiograms.…”

Section: Ethnicitymentioning

confidence: 96%

AMD: Epidemiology and Risk Factors

Khan¹

2013

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“…5−10 African-Americans with AMD have more peripapillary choroidal neovascularization than whites. 11 Neovascular AMD was more prevalent in the U.S. Beaver Dam and Australian Blue Mountain populations than in the European city of Rotterdam, Netherlands. 12,13 Geographic atrophy was more frequent in Chinese, Icelandic and Norwegian populations compared to other groups.…”

Section: Prevalencementioning

confidence: 97%

Review of Genetics in Age Related Macular Degeneration

Montezuma

Sobrin

Seddon

2007

Seminars in Ophthalmology

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Age-related macular degeneration (AMD) is a degenerative disease of the retina and the leading cause of blindness in industrialized countries. AMD is a complex disease caused by the combination of genetic predisposition and environmental factors. The prevalence of AMD increases with age. The adverse effect of smoking is well established. Genetic predisposition has been demonstrated by familial aggregation studies and twin studies. Using genome linkage scan and association studies, multiple potentially causative genes have been identified. The chromosomes most commonly implicated are 1q25-31 and 10q26. In particular, variants in the gene for the complement factor H (CFH) and the genes PLEKHA1/LOC387715/HTRA1, Factor B (BF) and complement component 2 (C2) have been implicated as major risk or protective factors for the development of AMD. There have been some advances in the treatment of this condition; however, a complete cure remains remote but hopeful. Understanding the causative environmental and genetic interactions will facilitate the development of future preventive methods and treatments.

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Symptomatic Choroidal Neovascularization in Blacks

Cited by 24 publications

References 22 publications

Treating peripapillary choroidal neovascular membranes: a review of the evidence

Treating peripapillary choroidal neovascular membranes: a review of the evidence

AMD: Epidemiology and Risk Factors

Review of Genetics in Age Related Macular Degeneration

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