Symptomatic benign multinodular goiter: Unilateral or bilateral thyroidectomy?

Olson, S.; Starling, James R.; Chen, Herbert

doi:10.1016/j.surg.2007.07.003

Cited by 46 publications

(50 citation statements)

References 14 publications

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“…Opponents of unilateral resection are concerned with the higher recurrence rates associated with this operation due to the presence of remaining thyroid tissue. Previous studies report a wide range of recurrence rates, from 1.5-34% [3,[10][11][12][13]. Given this risk, some surgeons prefer to perform a bilateral thyroidectomy in order to decrease the possibility of developing a recurrent goiter and, thus, avoid further surgical intervention.…”

Section: Introductionmentioning

confidence: 99%

“…Given this risk, some surgeons prefer to perform a bilateral thyroidectomy in order to decrease the possibility of developing a recurrent goiter and, thus, avoid further surgical intervention. Although the rate of recurrence is lower for bilateral resection, a more extensive surgery generally leads to higher rates of post-operative complications [1,3,8,[14][15][16]. The most common complications with thyroid resection are hematoma, voice hoarseness due to damage to the recurrent laryngeal nerve with subsequent vocal fold paralysis, permanent hypoparathyroidism, and transient hypocalcemia due to parathyroidal ischemia or inadvertent damage to the parathyroids [17].…”

Section: Introductionmentioning

confidence: 99%

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Unilateral Thyroidectomy for the Treatment of Benign Multinodular Goiter

Bauer

Murray

Clark

et al. 2013

Journal of Surgical Research

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BACKGROUND-Benign multinodular goiter (MNG) is one of the most commonly treated thyroid disorders. While bilateral resection is the accepted surgical treatment for bilateral MNG, the appropriate surgical resection for unilateral MNG continues to be debated. Bilateral resection generally has lower recurrence rates but higher complication rates than unilateral resection. Therefore, the purpose of this study was to define the recurrence and complication rates of unilateral and bilateral resections in order to determine the appropriate intervention for patients with unilateral, benign MNG.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Unilateral Thyroidectomy for the Treatment of Benign Multinodular Goiter

Bauer

Murray

Clark

et al. 2013

Journal of Surgical Research

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“…Surgery on the thyroid gland has usually been reserved for patients with goiters accompanied by obstructive manifestations, failed medical management, cosmetic problems and any clinical suspicion of malignant neoplasia [6,7]. The main concern is the potentially high rate of complications such as hematoma, permanent recurrent laryngeal nerve (RLN) paralysis and hypoparathyroidism [8,9]. A large or intrathoracic goiter, extensive malignancy, secondary procedure, inexperience of the surgical team and extent of the operation are the criteria that increase the complication rate [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

The Factors Related with Postoperative Complications in Benign Nodular Thyroid Surgery

et al. 2010

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Thyroid gland is an important endocrine organ because of its functions. Although the morbidity and mortality of thyroid surgery have decreased markedly, serious complications may still occur. The aim of this retrospective study was to identify the factors influencing the complications in benign nodular thyroid surgery. A total of 332 patients who underwent thyroid surgery between April 2004 and May 2008 were evaluated retrospectively to identify the factors influencing the complications. We found that in surgery lasting more than 90 minutes the risk of permanent recurrent laryngeal nerve (RLN) injury was high, daily drainage more than 50 cc increases the risk of seroma formation, retrosternal goiter surgery have higher risk for bleeding. The flap edema rates were high found in the operations made by resident surgeon and patients with size 3-4 thyroid glands. Low complication rates can be achieved after thyroidectomy with better knowledge of the surgical anatomy of the neck, thyroid pathology and required surgical treatment.

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“…On the other hand, there are some other investigations which avoided the TT method, because of its complications of persistent or temporary recurrent laryngeal nerve palsy and parathyroid damage [6,7]. These surgeons declare that BST or NTT methods are better because of presuming lower incidence of postoperative complications and the attempt to achieve postoperative euthyroid status earlier.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the results of total thyroidectomy and Dunhill operation in surgical treatment of multinodular goiter

et al. 2015

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Multi-nodular goiter (MNG) is one of the commonest thyroid gland disease. Surgery is an important treatment option in the presence of indications. There are several alternative procedures for thyroid gland operation such as subtotal thyroidectomy (STT), near-total thyroidectomy (NTT), hemi-thyroidectomy plus subtotal resection (Dunhill procedure), and total thyroidectomy (TT), but the surgical procedure of choice is still under discussion. In this study, 173 consecutive patients with multi-nodular goiter underwent thyroid operation in the department of surgery of Pursina Hospital in Rasht-Iran, using two different methods: Dunhill operation and total thyroidectomy. Outcome assessment was performed 4 days after surgery, 2 weeks, 1, 2, 10, and 20 month after surgery. Preoperative assessment, seroma, recurrent laryngeal nerve palsy, hypocalcaemia rates, and rates of other postoperative complications, final pathology, and recurrence were compared in two methods. Due to the high incidence of malignancy in this survey, TT can be the method of choice for MNG surgery. Also, TT will be more beneficial in the surgical treatment of benign thyroid disorders, especially those which are bilateral or extended to substernal space or which presented with compression symptoms.

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Symptomatic benign multinodular goiter: Unilateral or bilateral thyroidectomy?

Cited by 46 publications

References 14 publications

Unilateral Thyroidectomy for the Treatment of Benign Multinodular Goiter

Unilateral Thyroidectomy for the Treatment of Benign Multinodular Goiter

The Factors Related with Postoperative Complications in Benign Nodular Thyroid Surgery

Comparison of the results of total thyroidectomy and Dunhill operation in surgical treatment of multinodular goiter

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