Symptom Clusters Predict Mortality Among Dialysis Patients in Norway: A Prospective Observational Cohort Study

Abstract

Clustering of uremic symptoms predicted mortality. Assessing co-occurring symptoms rather than single symptoms may help to identify dialysis patients at high risk for mortality.

Fatores associados à qualidade de vida de pacientes renais crônicos em hemodiálise

“…Higher scores reflected better quality of life. (12) The collected data were uploaded into a Microsoft Office Excel™ spreadsheet by means of the Statistical Program for the Social Sciences (SPSS)™, and the analyses performed were: Kolmogorov-Smirnov, to verify the lack of data normality. Mann-Whitney test was used to compare the midpoints of HRQOL according to the categorical sociodemographic variables, Spearman correlation to analyze the relationship between the mean scores of HRQOL and sociodemographic, economic and numerical clinical variables; and logistic regression, for multivariate analysis with stepwise selection criterion variables used to describe the relationship between a dependent variable (HRQOL) and a simultaneous set of independent variables (education, gender, age, ethnicity, practicing a religion, marital status, and hematocrit).…”

Multidimensional symptom clusters: an exploratory factor analysis in advanced chronic kidney disease

“…) and mortality rate (Amro et al . ). Information about these correlations may be valuable to facilitate development of interventions that lead to improvements in patients' prognosis, functional status, quality of life and survival.…”

“…, Amro et al . , , Lee & Jeon ), although most of these studies occur in the final stage of CKD (i.e. end stage kidney disease).…”

Which Patients With Chronic Kidney Disease Have the Greatest Symptom Burden? A Comparative Study of Advanced CKD Stage and Dialysis Modality

“…; Davison & Jhangri ) and increased morbidity and mortality rates (Amro et al . ), likely through a reduction in treatment adherence (Davison & Jhangri ). Comprehensive reviews identify that the average number of symptoms per patients range between 6 to 20 symptoms (Almutary et al .…”

“…CKD creates a significant burden for individuals, often due to numerous troublesome symptoms, particularly in advanced stages of the disease (Abdel-Kader et al 2009;Caplin et al 2011). There is a growing body of evidence that CKD symptom burden is negatively correlated Health Related Quality of Life (HRQoL) (Jablonski 2007;Abdel-Kader et al 2009;Yong et al 2009;Davison & Jhangri 2010) and increased morbidity and mortality rates (Amro et al 2014), likely through a reduction in treatment adherence (Davison & Jhangri 2005). Comprehensive reviews identify that the average number of symptoms per patients range between 6 to 20 symptoms (Almutary et al 2013) and the most prevalent symptoms are fatigue, pain, pruritus, sleep disturbance and poor appetite (Almutary et al 2013;Murtagh et al 2007).…”