Sympathicotomy for Isolated Facial Blushing: A Randomized Clinical Trial

Licht, Peter B.; Pilegaard, Hans K.; Ladegaard, Lars

doi:10.1016/j.athoracsur.2012.03.076

Cited by 16 publications

(15 citation statements)

References 16 publications

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“…The meta-analysis included 11 RCT studies with a total of 1079 patients (585 in the experimental groups and 519 in the control groups), and 25 patients were enrolled in both an experimental group and a control group because they had undergone unilateral T2 and T3 ablation followed by contralateral ablation at level T2 only. Five of the RCTs studied restricting the level of sympathectomy 17-21 , and six studied lowering the level of sympathectomy 22-26 ( Table 1 ). Two of the studies did not report the exact number of severe CS patients 19 , 20 , and we obtained the unpublished results by e-mail.…”

Section: Resultsmentioning

confidence: 99%

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Compensatory sweating after restricting or lowering the level of sympathectomy: a systematic review and meta-analysis

Cai¹,

Shen²,

Li³

et al. 2015

Clinics

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OBJECTIVE:To compare compensatory sweating after lowering or restricting the level of sympathectomy.METHOD:A systematic review and meta-analysis were conducted of all randomized controlled trials published in English that compared compensatory sweating after lowering or restricting the level of sympathectomy. The Cochrane collaboration tool was used to assess the risk of bias, and the Mantel-Haenszel odds ratio method was used for the meta-analysis.RESULTS:A total of 11 randomized controlled trials were included, including a total of 1079 patients. Five of the randomized controlled trials studied restricting the level of sympathectomy, and the remaining six studied lowering the level of sympathectomy.CONCLUSIONS:The compiled randomized controlled trial results published so far in the literature do not support the claims that lowering or restricting the level of sympathetic ablation results in less compensatory sweating.

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Section: Resultsmentioning

confidence: 99%

“…ETS is used to treat not only PH but also facial blushing, facial hyperhidrosis, and axillary hyperhidrosis, among other conditions. Recently, several RCT studies on treating facial blushing and axillary hyperhidrosis have been published 9 , 10 .…”

Section: Introductionmentioning

confidence: 99%

Compensatory sweating after restricting or lowering the level of sympathectomy: a systematic review and meta-analysis

Cai¹,

Shen²,

Li³

et al. 2015

Clinics

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“…In Scandinavia, surgical treatment of blushing accounted for approximately half of all sympathectomies [77,85], whereas sympathetic ablation for this indication is quite rare in Asia [68]. The reason could be either a different cultural attitude to the problem or, possibly, a true constitutional difference between populations.…”

Section: Blushingmentioning

confidence: 99%

“…However, a recent randomized clinical study [85] comparing R2 versus R2-R3 sympathetic ablation did not show any significant difference in local effect.…”

Section: Blushingmentioning

confidence: 99%

Thoracic sympathectomy: a review of current indications

et al. 2015

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Currently, thoracic sympathetic ablation is indicated mainly for primary hyperhidrosis, especially affecting the palm, and to a lesser degree, axilla and face, and for facial blushing. Despite modern pharmaceutical, endovascular and surgical treatments, sympathetic ablation has still a place in the treatment of very selected cases of angina, arrhythmias and cardiomyopathy. Thoracic sympathetic ablation is indicated in several painful conditions: the early stages of complex regional pain syndrome, erythromelalgia, and some pancreatic and other painful abdominal pathologies. Although ischaemia was historically the major indication for sympathetic ablation, its use has declined to a few selected cases of thromboangiitis obliterans (Buerger's disease), microemboli, primary Raynaud's phenomenon and Raynaud's phenomenon secondary to collagen diseases, paraneoplastic syndrome, frostbite and vibration syndrome. Thoracic sympathetic ablation for hypertension is obsolete, and direct endovascular renal sympathectomy still requires adequate clinical trials. There are rare publications of sympathetic ablation for primary phobias, but there is no scientific basis to support sympathetic surgery for any psychiatric indication.

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“…Still, the first comprehensive study on excessive facial blushing was published by the Swedish 'Boras Group' in 1998 12,13 . Several papers addressing isolated treatment of excessive facial blushing and sweating by means of thoracoscopic sympathectomy [14][15][16][17][18][19][20][21][22] have been published since then, but the number of papers on this subject is far smaller than the number of those dealing with the primary focal hyperhidrosis (axillae, palms), and because a small number of surgeons perform thoracoscopic sympathectomy in patients with the isolated problem of excessive facial blushing and sweating 23 .…”

Section: Hyperhidrosismentioning

confidence: 99%