Symmetric Peripheral Gangrene in a Nigerian Woman: A Rare Complication of Unsafe Abortion

Symmetrical peripheral gangrene in a child following severe malaria with concomitant sepsis

“…1 As a result, many systemic conditions such as severe malaria, sepsis, tumour, septic abortion and drugs have been linked with its occurrence. 4,5,21,22 The convergence of sepsis and severe malaria, two of the most common predisposing factors, may explain the development of this rare condition in our patient. Both sepsis and severe malaria can independently predispose to SPG through microvascular obstruction and development of DIC.…”

“…Sepsis, particularly from bacterial infections is the leading cause of SPG. 4,11 Malaria remains endemic in this part of the world with Plasmodium falciparum being the causative agent of most cases of severe malaria. 9 Most of the cases of SPG arising as complications of malaria isolated Plasmodium falciparum in the peripheral blood.…”

“…1 Sepsis and very rarely, severe plasmodium falciparum malaria are the two leading infectious conditions linked with symmetrical peripheral gangrene. [1][2][3][4][5][6] Only a few published reports have highlighted the occurrence of SPG in children with severe malaria. 5,7 Malaria remains a common disease in tropical parts of the world and children below 5 years of age are the most affected, it is also one of the leading causes of mortality among them.…”