Symmetric facial macules in an Asian woman

Gaufin, Meredith; DiLorenzo, Ashley; Deng, Min; DeWitt, Christine A.; Cardis, Michael A.

doi:10.5070/d3273052779

Cited by 1 publication

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Histopathologically, Hori's nevus displays deeply pigmented melanocytes and melanophages in the superficial dermal layer, and is characterized by their elongated, slender, and irregularly shaped highly dendritic appearance 4 . Differential diagnoses include nevus of Ota, nevus of Ito, congenital dermal melanocytoses, melasma, and ephelides, which may coexist with Hori's nevus 2,5,6 …”

Section: Introductionmentioning

confidence: 99%

“…4 Differential diagnoses include nevus of Ota, nevus of Ito, congenital dermal melanocytoses, melasma, and ephelides, which may coexist with Hori's nevus. 2,5,6 Although the etiology of Hori's nevus remains unclear, there are three primary mechanisms believed to underlie its development. The first mechanism involves the migration of epidermal melanocytes and hair bulb melanocytes to the dermis, though the reasons for this migration remain elusive.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Exploring the potential of intradermal platelet‐rich plasma in treating acquired bilateral nevus of Ota‐like macule (Hori's nevus): A pilot study

Deeudomwongsa,

Chumsaengsri,

Aristizabal

et al. 2023

J of Cosmetic Dermatology

View full text Add to dashboard Cite

BackgroundHori's nevus is a common and challenging dermatological condition, often complicated by post‐inflammatory hyperpigmentation following treatment. Platelet‐rich plasma (PRP) has demonstrated efficacy in the treatment of hyperpigmentation disorders such as melasma and periorbital darkening. Given the benefits and minimally invasive nature of PRP treatments, exploring its application in managing Hori's nevus through further investigation is worthwhile.AimsTo evaluate the safety and effectiveness of intradermal PRP therapy for the treatment of Hori's nevus.MethodsTen female patients received bilateral intradermal PRP injections every 2 weeks for a total of four treatments. The modified dermal pigmentation and severity index (mDPASI), mean melanin index (MI), brightening score, patient self‐assessment, and clinical photographs were evaluated at 2, 4, 8, and 12 weeks post‐treatment. Adverse events were also recorded to determine treatment safety.ResultsAt 12 weeks post‐treatment, mDPASI decreased 38.86%, from 0.929 ± 0.617 to 0.568 ± 0.415 (p < 0.05). The mean melanin index decreased 12.75%, from 208.650 ± 26.319 to 182.052 ± 17.028 (p < 0.05). In addition, the mean brightness score evaluated by two experts was 1.4, indicating 25–50% improvement. At the end of the study, 50% of the patients reported 50–75% improvement. Side effects included pain, mild edema, and bruising, which resolved spontaneously within 3 days. No serious side effects were found.ConclusionOur results suggest that intradermal PRP therapy may be a safe and effective alternative for the treatment of Hori's nevus and can complement conventional interventions. However, further research with a larger sample size, control groups, and longer follow‐up is needed to confirm these findings.

show abstract

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%