Symbiotic collision tumour of the scalp: squamous cell carcinoma and malignant melanoma

Mangkorntongsakul, Varitsara; Tng, Er Tsing Vivian; Scurry, James; Gourlay, Ralph

doi:10.1111/ajd.13218

Cited by 4 publications

(3 citation statements)

References 3 publications

(7 reference statements)

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“…They speculate this may suggest interaction theory as the etiology of their tumor. 14 The prognosis of this rare tumor remains uncertain. 1 Many cases of SMT have been followed closely for years with no evidence of metastasis or recurrence.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Malignant Squamomelanocytic Tumor: A Case Report of a Rare Neoplasm

Zipperer

Good²,

Gibson³

et al. 2022

The American Journal of Dermatopathology

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Cutaneous squamomelanocytic tumor (SMT) is an exceedingly rare cutaneous malignancy characterized by the presence of both squamous cell carcinoma and malignant melanoma within a single tumor. SMT typically presents clinically as keratotic skin papulonodules, most commonly occurring on the face, scalp, or other sun-exposed areas of middle-aged to elderly White male patients. Owing to the rare nature of this tumor, the histogenesis and prognosis remain relatively unclear. Histopathological examination of the tangential biopsy revealed an invasive cutaneous malignancy consisting of 2 distinct yet closely associated atypical cell populations: (1) a population of atypical squamoid epithelial cells arranged in cords and keratin pearls and (2) a population consisting of atypical, spindled cells with fine melanin pigment arranged in confluent sheets. Both populations of atypical cells emanated in an invasive pattern from the underside of the overlying epidermis into the deep dermis. Squamomelanocytic tumors are among the rarer types of collision tumors between 2 malignant lesions as most are basomelanocytic. For most reported SMTs, the melanoma population comprises epithelioid cell morphology, whereas our tumor is composed of spindled cell morphology. In this article, we exemplify a unique case of SMT in an 87-year-old male patient.

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Section: Discussionmentioning

confidence: 99%

Cutaneous Malignant Squamomelanocytic Tumor: A Case Report of a Rare Neoplasm

Zipperer

Good²,

Gibson³

et al. 2022

The American Journal of Dermatopathology

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“…Collision tumors are tumors of different tissue origins that coexist in the same tissue or organ without histological fusion ( 3 ). Collision tumors have been reported in different parts of the body, including the skin, thyroid, uterus, brain, gastrointestinal tract, and genitourinary tract ( 4 – 6 ). Primary renal collision tumors are rare, and only sporadic cases have been reported in the medical literature.…”

Section: Discussionmentioning

confidence: 99%

Case report: A collision tumor of clear cell renal cell carcinoma and clear cell papillary renal cell tumor

Lin,

Guo,

et al. 2024

Front. Oncol.

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We report the case of a 51-year-old woman who was initially hospitalized in the respiratory department with cough and fever. Urinary computed tomography (CT) showed two different incidental masses in the right kidney. The patient underwent a radical right nephrectomy without lymph node dissection and postoperative adjuvant treatment. The pathological examination of the surgical specimens showed a collision tumor composed of a clear cell renal cell carcinoma (CCRCC) and a clear cell papillary renal cell tumor (CCPRCT). To the best of our knowledge, this is the first such case reported to date. No recurrence of local or distant metastasis was found during routine follow-up 14 months after the operation.

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“…In Cornejo and Deng's review, they identified three collision and two combined and collision tumors comprised of SCC and melanoma 5 . In 2019, Mangkorntongsakul et al described a case report of a large and recurrent ulcerating nodule excised from the scalp of a 70‐year‐old immunosuppressed patient who had a histopathologic diagnosis of a SCC and malignant melanoma collision tumor 16 …”

Section: Collision Tumor Typesmentioning

confidence: 99%

Collision tumors: A review of their types, pathogenesis, and diagnostic challenges

Bulte

Hoegler

Khachemoune

2020

Dermatologic Therapy

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A collision tumor is a neoplastic lesion comprised of two or more distinct cell populations that maintain distinct borders. Collision tumors, which are rare but well documented, can be composed of two benign tumors, a benign and malignant tumor, and two malignant tumors. Although case reports and reviews on specific types of collision tumors exist, a cohesive source discussing these tumors is lacking. We critically reviewed the literature by analyzing case reports and retrospective studies in order to evaluate the following regarding collision tumors: definitions, types, pathogenesis, diagnosis, and management. Reports of these tumors are infrequent but not insignificant, and accurate classification and diagnosis will lead to better patient outcomes.

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Symbiotic collision tumour of the scalp: squamous cell carcinoma and malignant melanoma

Cited by 4 publications

References 3 publications

Cutaneous Malignant Squamomelanocytic Tumor: A Case Report of a Rare Neoplasm

Cutaneous Malignant Squamomelanocytic Tumor: A Case Report of a Rare Neoplasm

Case report: A collision tumor of clear cell renal cell carcinoma and clear cell papillary renal cell tumor

Collision tumors: A review of their types, pathogenesis, and diagnostic challenges

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