“…[35,54,57,94,95] In as eparate body of non-delivery-related work, polymer-enzymeb inding was studied with respect to turning enzyme function on and off. [66,92,96,97] Taking advantage of this pre-existing body of knowledge,o ne could image correlation studies in which polymer-protein binding constants were measured by using enzymesa sc argo,f or which the activity could be subsequently monitored both in and outside of the cell. Correlations could then be drawn between polymer bindingi nt he complex-formations tage and cargo activity in the release stage.…”